Results 61 to 70 of about 1,154,997 (309)

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

MELK Inhibition Effectively Suppresses Growth of Glioblastoma and Cancer Stem-Like Cells by Blocking AKT and FOXM1 Pathways

Frontiers in Oncology, 2021
Glioblastoma multiforme (GBM) is a devastating disease yet no effective drug treatment has been established to date. Glioblastoma stem-like cells (GSCs) are insensitive to treatment and may be one of the reasons for the relapse of GBM. Maternal embryonic
Xu Zhang, Xu Zhang, Xu Zhang, Jie Wang, Jie Wang, Jie Wang, Yifeng Wang, Yifeng Wang, Guanzheng Liu, Huan Li, Jiefeng Yu, Runqiu Wu, Jun Liang, Rutong Yu, Rutong Yu, Xuejiao Liu, Xuejiao Liu   +16 more
doaj   +1 more source

The enteric nervous system in physiological and pathological conditions [PDF]

The enteric nervous system is a specific part of the autonomic nervous system, whose role is mainly concerned with ensuring the proper functioning of the gastrointestinal tract.
Tadeusz Kuder, Ilona Klejbor, Grzegorz Wróbel   +2 more
core   +1 more source

Central Nervous System Manifestations in Rheumatic Diseases [PDF]

, 2011
Central Nervous System Manifestations in Rheumatic DiseasesPatients with multi-system rheumatic conditions may have a disease affecting the central nervous system (CNS).
Camelia Vrabie, Isabela Silosi, Inimioara Cojocaru, Manole Cojocaru   +3 more
core   +1 more source

Infectious Diseases (esp. Equatorial): Infections of the Nervous System [PDF]

, 2022
Microbes, the most prevalent organisms on Earth, are essential parts of all ecosystems. We are all exposed to microbes in the environment and harbor them.
Kristensson, K, Rottenberg, M, Bentivoglio, M   +2 more
core   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction

Experimental Hematology & Oncology
Background Glioblastoma is a highly aggressive and devastating primary brain tumor that is resistant to conventional therapies. Oncolytic viruses represent a promising therapeutic approach for glioblastoma by selectively lysing tumor cells and eliciting ...
Yufu Zhu, Xuefeng Zhang, Jiaqi Jin, Xiaoqian Wang, Yang Liu, Jian Gao, Diancheng Hang, Lin Fang, Hengzhu Zhang, Hongmei Liu   +9 more
doaj   +1 more source

Spine and Spinal Cord Injuries on the Basis of Medical Documentation

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2014
Introduction. The progressive mechanisation of work in every area of life and the rapid development of means of transport have a major impact on the steadily increasing number of injuries.
Joanna Rosińczuk, Paweł Pietralik, Łukasz Wojciechowicz, Aleksandra Kołtuniuk   +3 more
doaj   +1 more source

Misperception of Body Weight After Childhood Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Misperception of body weight can negatively impact the weight management efforts of childhood cancer survivors (CCSs). Both being overweight or underweight are associated with chronic health conditions commonly observed in CCS; therefore, accurate weight perception is critical for reducing long‐term health risks.
Fabiën N. Belle, Tomáš Sláma, Eva Haegler‐Laube, Reto D. Kurmann, Gabriela M. Kuster, Christoph Saner, Eva Scheler, Yara Shoman, Christina Schindera   +8 more
wiley   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source