Results 91 to 100 of about 458,582 (324)
The origin and evolution of chordate nervous systems [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2015 In the past 40 years, comparisons of developmental gene expression and mechanisms of development (evodevo) joined comparative morphology as tools for reconstructing long-extinct ancestral forms. Unfortunately, both approaches typically give congruent answers only with closely related organisms. Chordate nervous systems are good examples.
openaire +4 more sources
Modeling Life as Cognitive Info-Computation [PDF]
, 2014 This article presents a naturalist approach to cognition understood as a network of info-computational, autopoietic processes in living systems. It provides a conceptual framework for the unified view of cognition as evolved from the simplest to the most
A. Zeilinger +19 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Animal Evolution: Looking for the First Nervous System [PDF]
Current Biology, 2014 The human brain is easily the most baffling bit of biology on the planet. How did the nervous system evolve? What came first: neurons or synaptic proteins? A new paper studying the pancake-shaped Trichoplax suggests it was not the neurons.
openaire +2 more sources
BMC Biology, 2018 Angelika Stollewerk is a Reader at Queen Mary University of London, where her lab uses a diverse range of species to study the evolution of the arthropod nervous system.
Angelika Stollewerk
doaj +1 more source
Subsea approach to work systems development [PDF]
Self-contained undersea working environments with applications to space station EVA environments are discussed. Physiological limitations include decompression, inert gas narcosis, high-pressure nervous system, gas toxicity, and thermal limitations. Work
Brown, C. E. +2 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The evolution of the serotonergic nervous system
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2000 The pattern of development of the serotonergic nervous system is described from the larvae of ctenophores, platyhelminths, nemerteans, entoprocts, ectoprocts (bryozoans), molluscs, polychaetes, brachiopods, phoronids, echinoderms, enteropneusts and lampreys.
openaire +3 more sources
SoxB2 in sea urchin development: implications in neurogenesis, ciliogenesis and skeletal patterning
EvoDevo, 2018 Background Current studies in evolutionary developmental biology are focused on the reconstruction of gene regulatory networks in target animal species.
Evgeniya Anishchenko +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source