Results 121 to 130 of about 458,582 (324)

Syncytial nerve net in a ctenophore adds insights on the evolution of nervous systems [PDF]

, 2023
Pawel Burkhardt, Jeffrey Colgren, Astrid Medhus, Leonid Digel, Benjamin Naumann, Joan J. Soto-Angel, Eva-Lena Nordmann, Maria Y. Sachkova, Maike Kittelmann   +8 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Syncytial nets vs. chemical signaling: emerging properties of alternative integrative systems

Frontiers in Cell and Developmental Biology, 2023
Leonid L. Moroz, Leonid L. Moroz
doaj   +1 more source

The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome ofAplysia

, 2022
Joshua Orvis, Caroline B. Albertin, Pragya Shrestha, Shuangshuang Chen, Melanie Zheng, Cheyenne J. Rodriguez, Luke J. Tallon, Anup Mahurkar, Aleksey V. Zimin, Michelle Kim, Kelvin J. Liu, Eric R. Kandel, Claire M. Fraser, Wayne S. Sossin, Thomas W. Abrams   +14 more
openalex   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study

International Journal of Biological Sciences, 2006
The cephalochordate amphioxus is the closest invertebrate relative to vertebrates. In this study, using HPLC technique, free L-amino acids (L-AAs) and D-aspartic acid (D-Asp) have been detected in the nervous system of the amphioxus Branchiostoma ...
doaj  

Cornichons: Evolution, AMPA receptor modulation, and emerging roles beyond the nervous system

Brain Disorders
Cornichons are auxiliary proteins that regulate the functions of AMPA receptors (AMPARs), which mediate fast excitatory transmission in the central nervous system.
Pratibha Bharti, Anshul Assaiya, Bhavya K Dawath, Janesh Kumar   +3 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Parent brain responses to child facial and vocal communication: What different methodologies reveal about parenting cognitions and practices as well as their moderation by parental status, gender, and culture as well as child characteristics

Neuroscience Research
Parenting is constituted of caregiving cognitions and practices, based in evolution and biology as well as culture and context, and lodged in nervous system structure and function. This narrative review first discusses parenting and an orientation toward
Marc H. Bornstein, Amir Gandjbakhche, Thien Nguyen, Gianluca Esposito   +3 more
doaj   +1 more source