Results 151 to 160 of about 142,834 (335)

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

open access: yesInterdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li   +10 more
wiley   +1 more source

Development of Novel Primers and Probes Based on its 2 Region Using Nested-PCR and DNA Hybridization Array for Candida Species Identification [PDF]

open access: yes, 2007
Sensitivity, specificity, simplicity, speed, and economy fairly well describe the desirable attributes of any clinical diagnostic test. In the mycology laboratory, the detection and differentiation of Candida species usually rely on the morphological ...
Chieng, David Ching Soo
core  

Semi-nested RT-PCR enables sensitive and high-throughput detection of SARS-CoV-2 based on melting analysis

open access: green, 2022
Thi Ngoc Anh Nguyen   +30 more
openalex   +2 more sources

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong   +4 more
wiley   +1 more source

A Novel 9‐Channel 1H, 3‐Channel 31P Radiofrequency Coil for Interleaved Multinuclear Studies of Human Calf Muscle at 7 T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a double‐tuned calf coil with excellent 1H and 31P performance to study muscle physiology by interleaved 1H/31P MRS and parallel imaging at 7 T. Methods The coil combines three 1H transceive dipoles, six 1H receive‐only loops and three 31P transceive loops, arranged in a nested, half‐cylindrical layout.
Veronika Cap   +8 more
wiley   +1 more source

Molecular phylogenetic and morphological analyses revealed a new species, Leucocoprinus roseus (Agaricaceae, Basidiomycota), from Punjab, Pakistan

open access: yesNordic Journal of Botany, EarlyView.
In this article, we describe a new fungal species, Leucocoprinus roseus, collected in Canal View Park, District Mandi Bahauddin, Punjab, Pakistan. The species is proposed as new based on detailed morphological observations and molecular phylogenetic analysis using nuclear ribosomal DNA internal transcribed spacer (nrITS) sequences.
Wajahat Akram   +7 more
wiley   +1 more source

Molecular identification of Anaplasma platys in cattle by nested PCR. [PDF]

open access: yesIran J Microbiol, 2023
Al-Saadi M, Al-Sallami D, Alsultan A.
europepmc   +1 more source

Seasonal variations in planktonic food web structure affect stability by shifting the distribution of energy fluxes

open access: yesOikos, EarlyView.
Seasonality in temperate ecosystems shapes species phenology, influencing interactions and food web structure. Variations in species richness and biomass affect trophic interaction strength, a crucial factor for community stability, which can be assessed through energy fluxes – an essential indicator of ecosystem function.
Simon Bazin   +4 more
wiley   +1 more source

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