Results 131 to 140 of about 1,037,260 (308)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

A Comparative Study of the Efficiency of the New Loop-Mediated Isothermal Amplification Assay and Routine Procedures for Diagnosis of Hepatitis C Virus

مجله دانشکده پزشکی اصفهان, 2014
Background: Hepatitis C virus (HCV) is a major cause of chronic liver disease and a public health problem. Therefore, rapid detection and management is important.
Mohammad Kargar, Azam Askari, Abbas Doosti, Sadegh Ghorbani-Dalini   +3 more
doaj  

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

A high-resolution nested PCR assay for genotyping

International Journal of Infectious Diseases
Objectives: To define a reproducibly specified TSA56 fragment that preserves genotype assignment relative to the full-length gene and to establish a standardized sequence-based genotyping workflow using nested PCR and phylogenetic assignment. Methods: We
Xianyao Yang, Gaowen Liu, Xiu Zou, Yang Liu, Xinlin Wu, Yingchao Chang, Li Liu, Xueshan Xia, Yue Feng   +8 more
doaj   +1 more source

Nested-PCR for detection of Brucella in milk

浙江大学学报. 农业与生命科学版, 2008
To detect Brucella inflection in milk, a nested-PCR assay was developed by designing outward-directed and inward-directed primers for omp25, omp31 and 16S rRNA genes of Brucella abortus, and optimizing the extraction of Brucella genomic DNA. The results show that two rounds of amplification with the two pairs of synthesized primers F4/R2 and F2D/R1U ...
DU Zhen-kun, GUO Jun-qing, ZHANG Miao-xian, XIANG Yu-yan, ZHOU Ji-yong   +4 more
openaire   +1 more source

DNA methods for the detection of Phytophthora cinnamomi from soil [PDF]

, 2006
This project assesses two aspects of DNA detection of Phytophthora species from soil samples. Firstly, a nested PCR protocol was established with both primary and nested PCR specific for P. cinnamomi detection. PCR amplification of P.
Anderson, Nari Michelle
core  

Nested PCR conditions for the IGF2 and XIST genes.

, 2015
Nested PCR conditions for the IGF2 and XIST genes.
Margot Alves Nunes Dode (820172), Alexandre Rodrigues Caetano (787323), Maurício Machaim Franco (820173), Naiara Milagres Augusto da Silva (820171), Ana Luíza Silva Guimarães (820170), Anelise dos Santos Mendonça (820169)   +5 more
core   +1 more source

Disturbance from restoration reseeding is associated with short‐term topsoil carbon loss and alters soil bacterial communities and functions in degraded alpine meadows of the Qinghai–Xizang Plateau

Grassland Research, EarlyView.
Restoration reseeding of degraded alpine meadows increased aboveground vegetation but was associated with short‐term topsoil carbon loss, coinciding with a microbial strategy shift from resident carbon‐preserving to carbon‐spending bacterial guilds. Abstract Background Restoration of degraded ecosystems is widely promoted as a nature‐based solution ...
Long‐Tao Zhu, Wen‐Min Shi, Guang‐Peng Qu, Xu Yin, Yong‐Kang Zhang, Ying‐Jie Sun, Zhen Luo, Wei Li, Chun‐Ping Zhang, Jie‐Jun Xi   +9 more
wiley   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Primer sequence for each VNTR marker amplified by nested PCR.

, 2015
Primer sequence for each VNTR marker amplified by nested PCR.
Yann Reynaud (503432), Julie Millet (127730), Christopher Brown (258061), Nalin Rastogi (674), Pierre Couppié (342022), David Couvin (130640), Eric Legrand (248989)   +6 more
core   +1 more source