Results 101 to 110 of about 12,800,448 (216)

Uncoupling proximal tubule ammoniagenesis from bicarbonate generation by <i>PCK1</i> deletion. [PDF]

Am J Physiol Renal Physiol
Lee HW, Nar R, Weiner ID.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Deep Learning for Protein Secondary-Structure Segmentation in Intermediate-Resolution Cryo-EM Maps: A Resolution-Stratified Benchmark Dataset and Controlled Evaluation. [PDF]

ACS Omega
Pial MER, Dehan FN, Sazzed S.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Equivariant conditional diffusion model for head and neck CT image synthesis from CBCT. [PDF]

Med Phys
Altalib A, Li C, Perelli A.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evaluation of <i>Rhinella marina</i> Extracts on the Effector Functions of Human Neutrophils. [PDF]

Biology (Basel)
Albiero LR, Lima VDS, Marzocchi-Machado CM, Tucci LFF, Sousa ACA, Rodrigues DJ, Pimenta LCF, Penhacek M, Horn MJDC, Gomes JH, Sinhorin VDG, Sinhorin AP.   +11 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET-Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage. [PDF]

Adv Sci (Weinh)
Meng J, Wang J, Zhang T, Fan X, Guo J, Zhao S, Sun W, Jiang P.   +7 more
europepmc   +1 more source

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