Results 61 to 70 of about 13,921 (178)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

open access: yesAdvanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy   +9 more
wiley   +1 more source

ecmtool: fast and memory-efficient enumeration of elementary conversion modes. [PDF]

open access: yesBioinformatics, 2023
Buchner B   +3 more
europepmc   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

Continuous Blooming of Convex Polyhedra

open access: yes, 2009
We construct the first two continuous bloomings of all convex polyhedra. First, the source unfolding can be continuously bloomed. Second, any unfolding of a convex polyhedron can be refined (further cut, by a linear number of cuts) to have a continuous ...
Demaine, Erik D.   +5 more
core  

Boosting Photovoltaic Respond Through Molecular Engineering in Organic Manganese (II) Bromide for High‐Sensitivity X‑Ray Detection

open access: yesAdvanced Science, EarlyView.
This work successfully synthesized novel 0D Mn2⁺‐based metal halides (MHs) PTA2MnBr4 and DMA2MnBr4 wafers by a precise molecular design the distance between Mn atoms. The larger PTA⁺ benzene ring structure reduces energy transfer. Importantly, the X‐ray detector based on PTA2MnBr4 wafers achieved the high sensitivity of 1122 µC Gyair−1 cm−2, an low LoD
Feifei Chai   +8 more
wiley   +1 more source

Isoreticular Synthesis of Mesoporous Metal‐Organic Polyhedra with Permanent Porosity to Gas and Water

open access: yesAngewandte Chemie, EarlyView.
In this work, we report the synthesis of two robust, mesoporous metal‐organic cages or polyhedra (MOCs/MOPs) using an isoreticular expansion approach. Among them, the largest mesoporous MOP captures up to 0.47 gwater·gMOP−1, displaying an S‐shaped water sorption isotherm with a hysteresis loop.
Alba Cortés‐Martínez   +12 more
wiley   +2 more sources

Fast‐Charging Lithium–Sulfur Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review explores strategies to overcome fast‐charging challenges in lithium‐sulfur batteries (LSBs). It covers key techniques to address LiPS shuttling, sluggish kinetics, and dendrite formation. The crucial role of battery components, catalysts, and electrode/separator modifications is analyzed.
Jakob Offermann   +6 more
wiley   +1 more source

Chemical Bond Covalency in Superionic Halide Solid‐State Electrolytes

open access: yesAngewandte Chemie, EarlyView.
Achieving high conductivity in halide solid‐state electrolytes requires understanding key factors for ionic diffusion. This study provides direct evidence that metal‐halide covalent bonding controls superionic transitions and enhances Li+ mobility. Tailoring covalency through composition, demonstrated via in situ studies and simulations on bromide ...
Jiamin Fu   +17 more
wiley   +2 more sources

Understanding the Metal‐Center Mediated Adsorption and Redox Mechanisms in a FeMn(NbTa)2O6 Columbite Material for Anion Exchange Membrane Water Electrolyzers

open access: yesAdvanced Energy Materials, EarlyView.
FeMn(NbTa)2O6‐columbite is a sustainable and high‐performance bifunctional electrocatalyst for anion exchange membrane water electrolyzers, comparable to benchmark catalysts. In situ XAS and DFT analysis show Fe/Mn sites exhibit higher OER activity due to reduced overpotentials and favorable O→OOH energetics. The Nb/Ta sites facilitate charge transfer,
Patrick M. Bacirhonde   +17 more
wiley   +1 more source

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