Results 101 to 110 of about 2,691,157 (256)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Ranking of Mutually Exclusive Investment Projects: How Cash Flow Differences can solve the Ranking Problem [PDF]
The discussion about the best method to be used in capital budgeting has been long and intensive. Differences between Net Present Value and Internal Rate of Return seem to cause everlasting problems, while especially the Internal Rate of Return often is ...
Christian Kalhoefer
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Shaping resilient flood control system design through net present value assessments. [PDF]
PLoS OneAl-Rawas G +5 more
europepmc +1 more source
How correlated are changes in banks' net interest income and in their present value? [PDF]
We use portfolios of passive investment strategies to replicate the interest risk of banks' banking books. The following empirical statements are derived: (i) Changes in banks' present value and in their net interest income are highly correlated ...
Memmel, Christoph
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Evaluating Biosimilar Development Projects: An Analytical Framework Utilizing Net Present Value. [PDF]
BiologicsRanbhor R, Kulkarni P.
europepmc +1 more source
Dynamic Tax Depreciation Strategies [PDF]
The tax depreciation decision potentially has significant impact on the prof- itability of firms and projects. Indeed, the depreciation method chosen for tax purposes affects the timing of tax payments, and, as a consequence, it also affects the after ...
De Waegenaere, A.M.B., Wielhouwer, J.L.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
FEASIBILITY OF INTEGRATING SHEEP AND CROPS WITH SMALLHOLDER RUBBER PRODUCTION SYSTEMS IN INDONESIA [PDF]
Diversified production systems are considered important tools for stabilizing the income of smallholder rubber producers in Indonesia. Based on empirical data collected from smallholder rubber producers in the Nucleus Estate Smallholder (NES) development
Deaton, Brady J., San, Nu Nu
core +1 more source