The value of tax shields is not equal to the present value of tax shields: A correction [PDF]
I correct some expressions in Fernández (2004) and provide a more general expression for the value of tax shields. This expression is the difference between the present values of two different cash flows, each with its own risk: the present value of ...
Fernandez, Pablo
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Historical perspective on net present value and equivalent annual cost [PDF]
Net present value and equivalent annual cost are two discounted cash flow criteria for comparing investment proposals. Why have accountants taken to net present value? Why do engineers readily use equivalent annual cost?
Jones, Thomas W., Smith, J. David
core +1 more source
BullVal$: An Integrated Decision-Support Tool for Predicting the Net Present Value of a Dairy Bull Based on Genetic Merit, Semen Production Potential, and Demographic Factors. [PDF]
Gorr AQ +3 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Lessons from the northern hake long-term management plan: Could the economic assessment have accepted it? [PDF]
An economic expert working group (STECF/SGBRE-07-05) was convened in 2007 for evaluating the potential economic consequences of a Long-Term Management Plan for the northern hake.
Da Rocha, José María +1 more
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Feasibility of Bifacial Photovoltaics in Transport Infrastructure
Around the world, large-scale bifacial photovoltaics (BPV) modules are increasingly being used to generate clean electricity, given the cost of manufacturing is becoming comparable to conventional monofacial PV modules.
Mehreen Saleem Gul +2 more
doaj +1 more source
An optimal procedure for the resource-constrained project scheduling problem with discounted cash flows and generalized precedence relations. [PDF]
In this paper, we study the resource-constrained project scheduling problem (RCPSP) with discounted cash flows and generalized precedence relations (further denoted as RCPSPDC-GPR).
De Reyck, B, Herroelen, Willy
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

