Results 21 to 30 of about 125 (92)

Long-term efficacy of psoriasis treatment with the IL-17A inhibitor netakimab by suppressing bacterial endotoxemia

Russian Journal of Skin and Venereal Diseases
BACKGROUND: Despite the high efficacy of targeted therapy in psoriasis, there is an increase in loss of response (escape phenomenon), including due to the formation of antibodies against biologicals. At the same time, the role of other factors is insufficiently studied.
Umidzhon A. Tadzihibayev, Edgem A. Batkaev, Albina V. Simonova, Olga S. Yatskova   +3 more
exaly   +2 more sources

Fibromyalgia in patients with psoriatic arthritis: Relationship with clinical features of the disease and dynamics of symptoms during therapy with adalimumab, netakimab and methotrexate

Nauchno-Prakticheskaya Revmatologiya
The aim – to study of the relationship between the prevalence and severity of fibromyalgia (FM) symptoms in patients with psoriatic arthritis (PsA) and the characteristics of the clinical course and type of therapy for PsASubjects and methods.
Andriy Petrov
exaly   +3 more sources

Netakimab for the treatment of psoriatic arthritis: 3-year results of the phase III BCD-085-8/PATERA study

Современная ревматология
This article presents the results of the 3-year use of netakimab (NTK), a monoclonal antibody against interleukin 17, in patients with psoriatic arthritis (PsA) as part of the phase III PATERA study.
T. V. Korotaeva, V. I. Mazurov, A. M. Lila, I. Z. Gaidukova, A. L. Bakulev, A. V. Samtsov, V. R. Khairutdinov, A. V. Zinkina-Orikhan, Yu. N. Linkova, A. V. Eremeeva   +9 more
doaj   +2 more sources

Efficacy and safety profile of 2-year netakimab treatment in patients with moderate-to-severe plaque psoriasis in terms of the randomized double-blind placebo-controlled BCD-085-7/PLANETA clinical trial [PDF]

Vestnik Dermatologii i Venerologii, 2022
Background. Netakimab, a recombinant humanized monoclonal antibody, specifically binding to IL-17 blocks its activity resulting in plaque psoriasis signs decrease.
Andrey I. Bakulev, Alexey V. Samtsov, Evgeny V. Sokolovskiy, Muza M. Kokhan, Marianna M. Khobeish, Vladislav R. Khairutdinov, Arfenya E. Karamova, Olga U. Olisova, Dmitry V. Ignatiev, Aleksandra N. Nikiforova, Antonina V. Artemeva, Arina V. Zinkina-Orikhan   +11 more
doaj   +1 more source

Resolution of the Scientific Council of Experts: “The place of netakimab, a new inhibitor of IL-17A, in the treatment of psoriatic arthritis

Научно-практическая ревматология, 2020
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article Editorial
doaj   +1 more source

Resolution of the Research Council of Experts on the place of netakimab, a new interleukin-17a inhibitor, in the therapy of ankylosing spondylitis

Научно-практическая ревматология, 2020
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article Editorial
doaj   +1 more source

Aktuelle Entwicklungen und Perspektiven bei Psoriasis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 4, Page 363-373, April 2023., 2023
Zusammenfassung Die Erforschung kaum einer anderen Erkrankung hat so grundlegend neue Erkenntnisse über immunologischen Regulationen und gleichzeitig eine derart rasante Entwicklung innovativer Therapien hervorgebracht wie das Studium der Psoriasis.
Michael P. Schön, Dagmar Wilsmann‐Theis   +1 more
wiley   +1 more source

Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis

Clinical &Translational Immunology, Volume 12, Issue 12, 2023., 2023
Non‐infectious uveitis has a range of ocular and systemic autoimmune and autoinflammatory causes. When the retina is involved, blood‐retinal barrier breakdown can lead to vision loss. Specific cytokines stand out as promoting intraocular inflammation. This article reviews the involvement of inflammatory cytokines – including tumour necrosis factor (TNF)
Lisia Barros Ferreira, Keryn A Williams, Giles Best, Cameron D Haydinger, Justine R Smith   +4 more
wiley   +1 more source

IL‐17: Balancing Protective Immunity and Pathogenesis

Journal of Immunology Research, Volume 2023, Issue 1, 2023., 2023
The biological role of interleukin 17 (IL‐17) has been explored during recent decades and identified as a pivotal player in coordinating innate and adaptive immune responses. Notably, IL‐17 functions as a double‐edged sword with both destructive and protective immunological roles.
Lu Sun, Lufei Wang, Bethany B. Moore, Shaoping Zhang, Peng Xiao, Ann M. Decker, Hom-Lay Wang, Baohui Xu   +7 more
wiley   +1 more source

Efficacy and safety assessment of netakimab in scalp psoriasis

Meditsinskiy sovet = Medical Council, 2023
Introduction. Scalp psoriasis is a common disease that has a long, recurrent course with severe desquamation, dryness and itching of the skin. The location of the pathological process in an aesthetically significant area, constant therapy leads to low satisfaction and adherence to treatment and, as a result, to a pronounced decrease in the quality of ...
M. I. Kurdina, N. G. Kolenko
openaire   +1 more source