Results 51 to 60 of about 125 (92)

Netakimab in the treatment of psoriatic erythroderma

Meditsinskiy sovet = Medical Council
Psoriasis is considered as system immunoassociated disease of the multifactorial nature with dominating value in development of genetic factors. Suffer псориазом from 2 to 7% of inhabitants of a planet. Psoriasis it is started, when environment factors activate plasmocytoid dentrid cages that leads to development numerous proinflammatory citokines ...
G. N. Tarasenko, I. V. Patronov
openaire   +1 more source

Netakimab in anti-tnF-naïve patients with psoriatic arthritis: subanalysis of patEra clinical trial

Consilium Medicum, 2020
Нетакимаб (НТК) – гуманизированное моноклональное антитело против интерлейкина-17А. Препарат зарегистрирован для лечения псориатического артрита (ПсА), анкилозирующего спондилита и бляшечного псориаза. В статье представлены результаты субанализа 24-недельного периода кли-нического исследования III фазы PATERA у пациентов с активным ПсА. Цель.
Tatiana V. Korotaeva, Aleksei V. Samtsov, Vladislav R. Khairutdinov, Andrei L. Bakulev, Vladimir V. Mladov, Anna V. Eremeeva, Arina V. Zinkina-Orikhan   +6 more
openaire   +1 more source

A modern view on the treatment of psoriatic disease. Experience in using genetically engineered biological therapy in patients with extensive moderate to severe psoriasis

Медицинский совет, 2022
The article presents a modern view on the pathogenesis of psoriasis, considers an approach to management of patients with extensive moderate to severe psoriasis, sets out the key features of treatment with genetically engineered biological drugs of ...
E. V. Svechnikova, S. E. Zhufina
doaj   +1 more source

Therapy of netakimab in nail psoriasis

Meditsinskiy sovet = Medical Council
Introduction. The nail psoriasis severity does not always correspond to the skin process intensity, but often correlates with a more severe, prolonged and aggressive course of the disease.Materials and methods. 48 adult patients (n = 48) with nail psoriasis were under observation.
M. I. Kurdina, N. G. Kolenko
openaire   +1 more source

Profiles of patients with psoriasis for appointment gene-engineering biological therapy — clinical justification

Vestnik Dermatologii i Venerologii, 2020
Psoriasis is a chronic immune-mediated disease with predominant damage to the skin and musculoskeletal system. This paper describes the clinical manifestations of psoriasis requiring a special therapeutic approach.
Alexander S. Zhukov, Alkes A. Khotko, Vladislav R. Khairutdinov, Aleksey V. Samtsov   +3 more
doaj   +1 more source

Pharmacoeconomic study of active psoriatic arthritis treatment

Фармакоэкономика
Objective: to conduct a clinical and economic analysis of the therapy for adult patients with psoriatic arthritis (PsA) using netakimab, a Russian interleukin-17 inhibitor, in comparison with other biological (b) and targeted synthetic (ts) disease ...
A. V. Rudakova, Т. V. Korotaeva
doaj   +1 more source

Clinical case: switching from basic therapy with methotrexate to therapy with netakimab, an IL-17 inhibitor, in a patient with severe psoriasis

Meditsinskiy sovet = Medical Council, 2023
Currently, psoriasis occupies a leading position in the structure of chronic recurrent dermatological diseases. The modern view on the etiopathogenesis of psoriasis allows us to consider this disease as a systemic, genetically determined, immune-mediated process, which manifests itself not only in the form of damage to the skin, but also leads to the ...
E. V. Svechnikova, S. E. Zhufina, M. A. Morzhanaeva   +2 more
openaire   +1 more source

Systemic treatment of psoriasis: from methotrexate to biologics

Vestnik Dermatologii i Venerologii, 2020
Psoriasis is one of the most frequent chronic inflammatory skin diseases and it has been of interest to many scientists for ages. The review presents data on all systemic treatment options, that are to date officially registered in Russian Federation for
Olga Yu. Olisova, Ekaterina M. Anpilogova   +1 more
doaj   +1 more source

Myeloid-derived suppressor cells as biomarkers of the effectiveness of therapy with new biological agents in axial spondyloarthritis

Медицинская иммунология, 2023
Innate immune cells, including myeloid cells — myeloid derived suppressor cells (MDSCs) — are supposed to play an important role in the pathogenesis of axial spondyloarthritis (AxSp).
T. V. Tyrinova, A. Yu. Morenkova, A. V. Fedorova, M. A. Tikhonova, N. A. Ilina, O. A. Chumasova, A. E. Sizikov   +6 more
doaj   +1 more source

COVID-19 Pneumonia in Patients with Chronic Myocarditis (HBV-Associated with InfarctLike Debute): Specifics of the Diseases Course, the Role of the Basic Therapy (Part II)

Рациональная фармакотерапия в кардиологии, 2020
Chronic infectious-immune myocarditis of severe course can potentially be considered as a factor that aggravates the course of new coronavirus disease (COVID-19) and increases the risk of adverse outcomes. The interaction of chronic myocarditis and COVID-
O. V. Blagova, N. V. Varionchik, M. M. Beraia, V. A. Zaidenov, E. A. Kogan, N. D. Sarkisova, A. V. Nedostup   +6 more
doaj   +1 more source