Results 61 to 70 of about 1,424 (149)

Drosophila Netrin-B controls mushroom body axon extension and regulates courtship-associated learning and memory of a Drosophila fragile X syndrome model

Molecular Brain, 2019
Mushroom body (MB) is a prominent structure essential for olfactory learning and memory in the Drosophila brain. The development of the MB involves the appropriate guidance of axon lobes and sister axon branches.
Huaixing Kang, Juan Zhao, Xuan Jiang, Guangxu Li, Wen Huang, Huili Cheng, Ranhui Duan   +6 more
doaj   +1 more source

Identification of novel pathogenicity loci in Clostridium perfringens strains that cause avian necrotic enteritis. [PDF]

PLoS ONE, 2010
Type A Clostridium perfringens causes poultry necrotic enteritis (NE), an enteric disease of considerable economic importance, yet can also exist as a member of the normal intestinal microbiota.
Dion Lepp, Bryan Roxas, Valeria R Parreira, Pradeep R Marri, Everett L Rosey, Joshua Gong, J Glenn Songer, Gayatri Vedantam, John F Prescott   +8 more
doaj   +1 more source

Molecular architecture and functional analysis of NetB, a pore-forming toxin from Clostridium perfringens [PDF]

, 2013
NetB is a pore-forming toxin produced by Clostridium perfringens and has been reported to play a major role in the pathogenesis of avian necrotic enteritis, a disease that has emerged due to the removal of antibiotics in animal feedstuffs.
Cole, Ambrose R., Titball, R.W., Bokori-Brown, M., Naylor, Claire E., Fernandes da Costa, S.P., Moss, David S., Basak, Ajit K., Savva, Christos G.   +7 more
core   +1 more source

Necrotic Enteritis-Derived Clostridium perfringens Strain with Three Closely Related Independently Conjugative Toxin and Antibiotic Resistance Plasmids

mBio, 2011
The pathogenesis of avian necrotic enteritis involves NetB, a pore-forming toxin produced by virulent avian isolates of Clostridium perfringens type A.
Trudi L. Bannam, Xu-Xia Yan, Paul F. Harrison, Torsten Seemann, Anthony L. Keyburn, Christopher Stubenrauch, Lakmini H. Weeramantri, Jackie K. Cheung, Bruce A. McClane, John D. Boyce, Robert J. Moore, Julian I. Rood   +11 more
doaj   +1 more source

Anticoccidial Vaccination Is Associated with Improved Intestinal Health in Organic Chickens

Veterinary Sciences, 2022
Eimeria spp. and Clostridium perfringens (CP) are pathogens associated with coccidiosis and necrotic enteritis (NE) in broiler chickens. In this study we evaluated the effect of anticoccidial vaccination on intestinal health in clinically healthy organic
Désirée S. Jansson, Johan Höglund, Elisabeth Bagge, Tomas Jinnerot, Magne Kaldhusdal   +4 more
doaj   +1 more source

Variable protection against experimental broiler necrotic enteritis after immunisation with the C-terminal fragment of Clostridium perfringens alpha-toxin and a non-toxic NetB variant [PDF]

, 2016
Necrotic enteritis toxin B (NetB) is a pore-forming toxin produced by Clostridium perfringens and has been shown to play a key role in avian necrotic enteritis (NE), a disease causing significant costs to the poultry production industry worldwide.
Geeraerts, S, Titball, Richard, Mot, D, Geeraerts, Sofie, Bokori-Brown, Monika, Bokori-Brown, M, Mot, Dorien, Fernandes da Costa, SP, Van Immerseel, F, Van Immerseel, Filip, Geeraerts, SofieUGent0020030435328020007555259796205122370000-0003-0100-60790B491588-F0EE-11E1-A9DE-61C894A0A6B4, Mot, DorienUGent002003110119802000831509979420057188163FAB46-F0EE-11E1-A9DE-61C894A0A6B4, Van Immerseel, FilipDI058010013765480000-0003-0455-3350F5D28EA0-F0ED-11E1-A9DE-61C894A0A6B4, Fernandes da Costa, SergioUGent802001696425978030431249ACD9DC76-5ADC-11E3-88C2-00AE10BDE39D, Fernandes da Costa, Sergio, Titball, RW   +15 more
core   +1 more source

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

Animal Microbiome, 2019
Background Clostridium perfringens is a key pathogen in poultry-associated necrotic enteritis (NE). To date there are limited Whole Genome Sequencing based studies describing broiler-associated C. perfringens in healthy and diseased birds.
Raymond Kiu, Joseph Brown, Harley Bedwell, Charlotte Leclaire, Shabhonam Caim, Derek Pickard, Gordon Dougan, Ronald A. Dixon, Lindsay J. Hall   +8 more
doaj   +1 more source

The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens

, 2010
Clostridium perfringens causes several diseases in domestic livestock, including necrotic enteritis in chickens, which is of concern to the poultry industry due to its health implications and associated economic cost. The novel pore-forming toxin NetB is
Lanckriet, Anouk, Moore, Robert J, Rood, Julian I, Van Immerseel, FilipDI058010013765480000-0003-0455-3350F5D28EA0-F0ED-11E1-A9DE-61C894A0A6B4, Keyburn, Anthony L, Cheung, Jackie K, Carter, Glen P, Van Immerseel, Filip, Lanckriet, AnoukUGent801001989163001999169592052731245282919018850235F795F31C-F0ED-11E1-A9DE-61C894A0A6B4   +8 more
core   +1 more source

Prevalence and Genetic Diversity of Toxin Genes in Clinical Isolates of Clostridium perfringens: Coexistence of Alpha-Toxin Variant and Binary Enterotoxin Genes (bec/cpile)

Toxins, 2019
Clostridium perfringens (C. perfringens) is responsible for food-borne gastroenteritis and other infectious diseases, and toxins produced by this bacterium play a key role in pathogenesis. Although various toxins have been described for C.
Asami Matsuda, Meiji Soe Aung, Noriko Urushibara, Mitsuyo Kawaguchiya, Ayako Sumi, Mayumi Nakamura, Yuka Horino, Masahiko Ito, Satoshi Habadera, Nobumichi Kobayashi   +9 more
doaj   +1 more source

Prevalence of netB-positive Clostridium perfringens in Italian poultry flocks by environmental sampling

, 2019
Clostridium perfringens type G is one of the pathogens involved in enteric diseases in poultry. NetB, a poreforming toxin, is considered the main virulence factor responsible for necrotic enteritis during C. perfringens infection. We carried out a field
Scacchia, Massimo, Di Provvido, Andrea, Alessiani, Alessandra, Di Francesco, Cristina E., Marruchella, Giuseppe, Di Giannatale, Elisabetta, Orsini, Massimiliano, Marsilio, Fulvio, Profeta, Francesca, Toscani, Tonino   +9 more
core   +1 more source