Results 201 to 210 of about 19,431 (234)

DNA demethylation increases NETosis

Archives of Biochemistry and Biophysics, 2020
Neutrophil extracellular traps (NETs) occur during the development of autoimmune diseases, cancer and diabetes. A novel form of cell death that is induced by NETs is called NETosis. Although these diseases are known to have an epigenetic component, epigenetic regulation of NETosis has not previously been explored.
Hiroyuki Yasuda, Yutaka Takishita, Akihiro Morita, Tomonari Tsutsumi, Masahiko Tsuchiya, Eisuke F. Sato   +5 more
openaire   +2 more sources

NETosis, complement, and coagulation: a triangular relationship [PDF]

Cellular and Molecular Immunology, 2018
NETosis is a regulated form of neutrophil cell death that contributes to the host defense against pathogens and was linked to various diseases soon after its first description in 2004. During NETosis, neutrophils release neutrophil extracellular traps (NETs), which can capture and kill bacteria and other pathogens to prevent them from spreading ...
Ger J M Pruijn
exaly   +4 more sources

NETosis in Acute Thrombotic Disorders

Seminars in Thrombosis and Hemostasis, 2023
AbstractThe release of extracellular traps by neutrophils (NETs) represents a novel active mechanism of cell death that has been recently implicated in the pathogenesis of thrombotic disorders. The aim of this study was to investigate the generation of NETs in different groups of patients with acute thrombotic events (ATEs) and to establish whether ...
Bressan A., Faggin E., Donato M., Tonon L., Buso R., Nardin C., Tiepolo M., Cinetto F., Scarpa R., Agostini C., Pauletto P., Ventura L., Fusaro M., Felice C., Rattazzi M.   +14 more
openaire   +2 more sources

Induction and Quantification of NETosis

Current Protocols in Immunology, 2016
AbstractNeutrophil extracellular traps (NET) are web‐like structures composed of nuclear material and neutrophil granular proteins that are released to the extracellular space after specific microbial or sterile inflammatory stimuli. NETosis is a specific type of cell death that ensues when neutrophils extrude NETs. It is important to develop validated
Carmelo, Carmona-Rivera, Mariana J, Kaplan   +1 more
openaire   +2 more sources

An exploratory look at NETosis in atherosclerosis

Internal and Emergency Medicine, 2016
Current evidence suggests the likelihood of a link between venous thromboembolism (VTE) and atherosclerosis, although they have been traditionally considered as different pathological entities. The contribution of neutrophils to human atherogenesis has been underestimated, if compared to their contribution established in VTE.
MOZZINI, Chiara, GARBIN, Ulisse, FRATTA PASINI, Anna Maria, COMINACINI, Luciano   +3 more
openaire   +3 more sources

Reactive Oxygen Species, Granulocytes, and NETosis

2014
When pathogens invade the body, neutrophils create the first line of defense. Basic weaponry consists of phagocytosis and degranulation, but these cells have yet another ace in the sleeve, a unique strategy in which invading microorganisms are being destroyed.
Magdalena, Araźna, Michał P, Pruchniak, Urszula, Demkow   +2 more
openaire   +2 more sources

Implications of NETosis in Diabetic Wound Healing

Current Pharmaceutical Design

Md. Sadique Hussain, Ajay Singh Bisht, Gaurav Gupta   +2 more
openaire   +2 more sources

NETosis

Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology, 2019
openaire   +2 more sources

Farklı Yönleriyle Netosis

Gelişmiş ve gelişmekte olan ülkelerde otoimmün ve otoinflamatuar hastalıkların görülme sıklığında ciddi bir artış vardır. Bu hastalıkların etiyolojisi karmaşık ve multifaktöriyel nedenlere bağlı gelişmektedir. Sistemik otoimmün hastalıkların temelinde otoantijenler olduğu düşünülmektedir.
SÜRSAL, Neslihan, YILDIZ, Kader
openaire   +1 more source

A Tandem‐Locked Fluorescent NETosis Reporter for the Prognosis Assessment of Cancer Immunotherapy

Angewandte Chemie - International Edition, 2023
Kanyi Pu
exaly