Results 151 to 160 of about 25,958 (254)

Setting research priorities around the impact of COVID-19 control measures on people with dementia and caregivers living at home: A 14-country perspective. [PDF]

J Alzheimers Dis
Peeters G, Fitzpatrick RL, Mollayeva T, Chen Y, de Paula França Resende E, Leon T, Zapata-Restrepo LM, Tituaña K, Tsolaki M, Arshad F, Thapa P, Farombia T, Custodio B, Ntokozo Ngcobo K, O'Sullivan R, Leroi I, STRAP consortium.   +16 more
europepmc   +1 more source

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

Advanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller, Philip Maier, Dustin Vivod, Wenke Müller, Nikolaj Lopatik, Theresa Maria Schichtl, Julia Fröhlich, Irene Kraus, Marten Huck, Wieland Corts, Clodomiro Cafolla, Lukas Ruhm, Henrik Gaß, Johannes Voß, Jiwon Byun, Linda Rockmann, Guido Grundmeier, Kislon Voïtchovsky, Hans‐Georg Steinrück, Erdmann Spiecker, Sevim Dalabasmaz, Monika Pischetsrieder, Eike Brunner, Ralf Schweins, Dirk Zahn, Marcus Halik   +25 more
wiley   +1 more source

A research agenda for hypertensive disorders in pregnancy in Ghana through a priority setting partnership. [PDF]

Commun Med (Lond)
van Duijvendijk D, Arhin JK, Koi-Larbi K, Dodds LV, Obiri D, Beyuo TK, Srofenyoh E, van Vliet R, Boamah Amponsah S, Fynn P, Owusu-Bempah A, Milota M, Adu-Bonsaffoh K, Browne J, HDP PSP Advisory Committee.   +14 more
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

A Research Agenda for Acute Pediatric Mental and Behavioral Health Emergencies. [PDF]

Ann Emerg Med
Hoffmann JA, Foster AA, Krass P, Ibrahim SA, Huston S, Babcock L, Cafferty R, Duffy SJ, Ketabchi BW, Li K, McClain B, Mullan P, Patel SJ, Pitetti RD, Rogers SC, Saidinejad M, Uspal NG, Wong AH, Grupp-Phelan JM, Pediatric Emergency Care Applied Research Network Mental Health Working Group.   +19 more
europepmc   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Co-design in action: lessons learned from transplant patient and family engagement in an integrated knowledge translation strategy during the COVID-19 pandemic. [PDF]

Res Involv Engagem
Cameranesi M, Logan S, de Vries R, Escoto M, Hébert MJ, Kabbani D, Piotrowski C, West L, Gongal P, Canadian Donation and Transplantation Research Program.   +9 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Global research priorities for back pain, neck pain and osteoarthritis: a scoping review. [PDF]

BMJ Open
Young JJ, Pedersen JR, King LK, Zywiel M, Perruccio AV, Chandran V, Rampersaud YR, Hawker G, Briggs AM, Hartvigsen J, Koes B.   +10 more
europepmc   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source