Results 161 to 170 of about 577,979 (302)

Improving prehospital and emergency care for patients with mental dysregulation: a comprehensive research agenda. [PDF]

Scand J Trauma Resusc Emerg Med
Galenkamp N, van de Glind G, Schut B, Baden D, Singendonk MMJ, Werner L, van Veen M, Schoonhoven L, Scheepers FE, Blom-Ham WHW.   +9 more
europepmc   +1 more source

AI‐Assisted Self‐Powered Wearable Dual‐Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics

Advanced Science, EarlyView.
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li, Han Liu, Guoxu Liu, Qian'ao Wang, Haotian Zhou, Guiyi Liu, Yan Xu, Jun Wang, Zuqiang Wang, Feng Zhu, Feiling Luo, Zhong Lin Wang, Chi Zhang   +12 more
wiley   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

The dilemma of coordinated communication in China's e-cigarette governance: A computational discourse analysis of a social media controversy. [PDF]

Tob Induc Dis
Li Z, Zhao Y, Wang X, Gao L, Yao X, Chen Y.   +5 more
europepmc   +1 more source

Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials

Advanced Science, EarlyView.
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan, Hengheng Zhao, Haotian Wang, Zhanjie Liu, Qian Li, Weifeng Zhang, Qingsong Zhao, Liqun Zhang, Jun Liu   +8 more
wiley   +1 more source

Research priorities in pleural disease: study protocol for a joint patient-provider Delphi consensus statement. [PDF]

BMJ Open Respir Res
Shaw JA, Milne A, Mei F, Bodtger U, Walker SP.   +4 more
europepmc   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Cystic fibrosis learning network telehealth innovation lab during the COVID-19 pandemic: a success QI story for interdisciplinary care and agenda setting

BMJ Open Quality, 2022
, Rachel Gordon, Lucinda Murphy, Gregory Sawicki, Michael Seid, Rebekah Brown, Preeti Sharma, Maria T Britto, Christian Merlo, Peter Michelson, Jordan Dunitz, Christopher M Siracusa, Raouf S Amin, Thida Ong, Ahmet Uluer, Joanne Cullina, Sydney Schiff, Rhonda List, Lindsay Somerville, Lauren Williamson, Dana Albon, Hossein Sadeghi, Nicholas Antos, Fadi Asfour, Mike Price, Lacrecia Thomas, Lindsay Hoberg, Sophia Stamper, Prigi Varghese, Ella Balasa, Matthew Roman, Melanie Miner, Emily Gehring, Clifford Gammon, Mike Powers, Cori Daines, Glenda Drake, Amy Lucero, Lilly Mees, Amanda Sharpe, Lindsey McMahon, Melanie Abdelnour, Meghan Murray, Meghana Sathe, Traci Liberto, Rachel Linnemann, Alexia Hernandez Cargal, Heather Tucker, Pornchai Tirakitsoontorn, Maivy Sou, Alicia Maciel, Michael Schechter, Andrea Molzhon, Nicole Brueck, Karen Wunschel, Lisa A Mullen, Kyle Traver, Travis Burgett, Alex Gifford, Nicola Felicetti, Heidi Dolan, Tracey Gendreau, Danielle Beachler, Shine-Ann Pai, Stephanie Robbins, Zoe Orcutt, Ben McCullar, Lindsaey Deveaux, Lauren Mitchell, Andrew Scaljon, Stefanie Rushing, Virginia Birnbaum, Golnar Raissi, Bean Corcoran, Michelle Prickett, Rachel Nelson, Anne Snuggerud, Stacy Allen, Sabrina Gorry, Lisa Greene, Sara Renschen, Betsy Price, Catherine Kier, Teresa Carney, Sandy Corr, Barbara Leyva, Jillian Salvatore, George M Solomon, Julianna Bailey, James Lawlor, Samya Z Nasr, Rebekah Raines, Catherine Enochs, Kristen Jesse, Kayla Warner, Jonathan Flath, Mackenzie Wharram, Deborah Froh, Holly Carroll-Owens, James Tolle, Susan Eastman, Marrisa Benchea, Nauman Chaudary, Mahsa Farsad, Kimberly Wingo, Kathryn Moffett, Erin Brozik, Jillian Huffman   +107 more
doaj   +1 more source