Results 91 to 100 of about 1,291,783 (267)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Train Network Control of Trailer Free Marshalling DMUs
机车电传动, 2017 Aiming at the problems of trailer free marshalling, the application research of mutual redundancy of MVB bus and Ethernet bus on Ghana DMUs network control system was expounded, focusing on system design characteristics, network structure, network ...
XING Yuehua +4 more
doaj
Discrete Dynamics in Nature and Society, 2016 A modified fractional-order Chua chaotic circuit is proposed in this paper, and the chaotic attractor is obtained for q=0.98. Based on the Mittag-Leffler function in two parameters and Gronwall’s Lemma, two control schemes are proposed to stabilize the ...
Chunde Yang, Hao Cai, Ping Zhou
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Electric System of Changsha Metro Line 2 Battery Electric Vehicle
机车电传动, 2015 The basic characteristic of the battery electric vehicle of the Changsha metro line 2 were described. Main composition and characteristics of the electric drive system, auxiliary power supply system and network control system were introduced, and the ...
QIAO Xianhua, CHEN Xinjian, LI Ning
doaj
Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance
mBioDistinguishing hypervirulent (hvKp) from classical Klebsiella pneumoniae (cKp) strains is important for clinical care, surveillance, and research. Some combinations of iucA, iroB, peg-344, rmpA, and rmpA2 are most commonly used, but it is unclear what ...
Thomas A. Russo +13 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Network Control System Upgrade and Reconnection Modificationof CCQG Light Railway Vehicle
机车电传动, 2014 Control principle, merits and drawbacks of CCQG light railway vehicle existing network control system were expounded, andbased above, upgrade and reconnection modification scheme was presented.
ZHOU Xiao +3 more
doaj
Water Network Loss Control System
Engineering ProceedingsThis study addresses the issue of water losses in drinking water distribution networks, a problem exacerbated by climate change, drought, and aging infrastructure.
Silvie Drabinová +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source