Results 51 to 60 of about 1,281,547 (267)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
IEEE Access, 2019 In order to further solve the stability problem in the actual network control systems, this paper first simultaneously considers the controlled object system delay and network time delay in the Lurie nonlinear stochastic network control systems.
Hongqian Lu, Chaoqun Guo, Yue Hu
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Modelado de un network control system con retardos en la transmisión
Ciencia e Ingeniería, 2017 En este artículo se presenta un nuevo método de diseño de Modelo de Network Control System (NCS) con retardos en la transmisión. Este método parte de un modelado del NCS usando variables de estado en el dominio del tiempo, en el que se ha revisado todas ...
Sergio Velásquez +2 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Application of RAMS in Network Control System Designing of Rail Vehicles
机车电传动, 2012 RAMS element relationship, structure and the component functions of the rail vehicle network control system were analyzed. RAMS designing method for network control system was introduced, including availability designing, reliability asigning and ...
TANG Xian-kang +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Medium-low Speed Maglev Train Control and Network System
机车电传动, 2012 Design and configuration of network control system for medium-low speed maglev train were presented. Network control system was described from system bus, topology, and functions, etc.
SU Ai-jun +4 more
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