Results 121 to 130 of about 21,554,636 (317)

A Novel Design Approach for 5G Massive MIMO and NB-IoT Green Networks Using a Hybrid Jaya-Differential Evolution Algorithm

IEEE Access, 2019
Our main objective is to reduce power consumption by responding to the instantaneous bit rate demand by the user for 4th Generation (4G) and 5th Generation (5G) Massive MIMO network configurations.
Sotirios K. Goudos, Margot Deruyck, David Plets, Luc Martens, Kostas E. Psannis, Panagiotis Sarigiannidis, Wout Joseph   +6 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Prepositioning network design for humanitarian relief purposes under correlated demand uncertainty. [PDF]

Comput Ind Eng, 2023
Zhang X, Chen D.
europepmc   +2 more sources

Designing a Power and Speed Adaptive 60 GHz Receiver in 22 nm FD-SOI CMOS for Tactile Internet Applications

IEEE Access
This research presents and examines the first power and speed adaptive 60 GHz receiver, combining the potential of high data rates with low energy consumption.
Helmuth P. E. Morath, Xin An, Matthias Jobst, Mengqi Cui, Jens Wagner, Christian Mayr, Frank Ellinger   +6 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers

IEEE Access
In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. When options for improving active state efficiency are eventually exhausted, the next step is to aggressively minimize the duration a ...
Maximilian Gottfried Becker, Marco Gunia, Diego Mendez, Frank Ellinger   +3 more
doaj   +1 more source

Designing a Rational Distribution Network for Trading Companies

Transport and Telecommunication, 2017
This article considers the modern methods and approaches to design the company’s distribution network. The authors point out the relevance of this problem for the modern trading and manufacturing companies, give examples of the strategic goal setting of ...
Dybskaya V. V., Sverchkov P. A.
doaj   +1 more source

Liner shipping network design

European Journal of Operational Research, 2020
Marielle Christiansen, E. Hellsten, David Pisinger, David Sacramento, Charlotte Vilhelmsen   +4 more
semanticscholar   +1 more source