Results 101 to 110 of about 140,466 (301)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Constrained Consistency Modeling for Attributed Network Embedding
IEEE Access, 2019 Network embedding has emerged as a fundamental approach to network analysis tasks. Its main purpose is to learn a suitable mapping function to convert nodes in networks into a low-dimensional representations.
Xuan Zang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Constrained dynamic virtual network embedding
, 2023 International audienceThis paper focuses on a dynamic embedding ofclient-constrained heterogeneous Virtual Network (VN) requestswith multiple nodes and links anti-affinity requirements.
Hadji, Makhlouf +2 more
core +1 more source
Virtual network embedding method based on node delay perception
IET NetworksWireless virtual network uses software defined network and network function virtualisation technologies to create multiple logically isolated virtual networks on a physical wireless network.
Yaning Wang, Hui Zhi
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Spectral Embedding of Graph Networks
CoRR, 2020 We introduce an unsupervised graph embedding that trades off local node similarity and connectivity, and global structure. The embedding is based on a generalized graph Laplacian, whose eigenvectors compactly capture both network structure and neighborhood proximity in a single representation. The key idea is to transform the given graph into one whose
Shay Deutsch, Stefano Soatto
openaire +2 more sources
Nonlinear Dynamic Field Embedding: On Hyperspectral Scene Visualization
, 2012 In many areas of research, complex signals are commonly represented by high dimensional feature vectors. However, high dimensional vectors are difficult to analyze and interpret due to the curse of dimensionality.
Lunga, Dalton, Erosy, Okan
core
Multi-View Network Representation Learning Algorithm Research
Algorithms, 2019 Network representation learning is a key research field in network data mining. In this paper, we propose a novel multi-view network representation algorithm (MVNR), which embeds multi-scale relations of network vertices into the low dimensional ...
Zhonglin Ye +3 more
doaj +1 more source