Results 111 to 120 of about 140,466 (301)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Compact network embedding for fast node classification
, 2023 Network embedding has shown promising performance in real-world applications. The network embedding typically lies in a continuous vector space, where storage and computation costs are high, especially in large-scale applications.
Liu, Weiwei +5 more
core +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Optimal virtual network embedding: Node-link formulation
, 2013 Network Virtualization is claimed to be a key component of the Future Internet, providing the dynamic support of different networks with different paradigms and mechanisms in the same physical infrastructure. A major challenge in the dynamic provision of
Killat, Ulrich +4 more
core
On the computational complexity of the virtual network embedding problem [PDF]
, 2016 Given a graph representing a substrate (or physical) network with node and edge capacities and a set of virtual networks with node capacity demands and node-tonode traffic demands, the Virtual Network Embedding problem (VNE) calls for an embedding of (a ...
Coniglio, Stefano
core +1 more source
Inter-domain Virtual Network Embedding Policy for Revenue Maximization
工程科学与技术, 2018 Virtual network embedding algorithm mainly focus on the problem of how to carry more virtual networks on the substrate network by reasonably allocating resources.Inter-domain embedding is able to offer more substrate resources for virtual networks.On the
Yiming JIANG +4 more
doaj
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
, 2011 textScalable and accurate analysis of networks is essential to a wide variety of existing and emerging network systems. Specifically, network measurement and analysis helps to understand networks, improve existing services, and enable new data-mining ...
Song, Han Hee, 1978-
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source