Results 141 to 150 of about 2,811,322 (306)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Synergistic Two-Color Photochemical Polymer Network Formation and Lithography. [PDF]

open access: yesAngew Chem Int Ed Engl
Hobich J   +8 more
europepmc   +1 more source

The C. elegans DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance

open access: gold, 2013
Simona Rosu   +6 more
openalex   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Development and Optimisation of Hydrogel Scaffolds for Microvascular Network Formation. [PDF]

open access: yesBioengineering (Basel), 2023
Fuenteslópez CV, Thompson MS, Ye H.
europepmc   +1 more source

Potential maximizers and network formation

open access: yes, 1998
In this paper we study the formation of cooperation structures in superadditive cooperative TU-games.Cooperation structures are represented by hypergraphs.The formation process is modelled as a game in strategic form, where the payoffs are determined according to a weighted (extended) Myerson value.This class of solution concepts turns out to be the ...
Slikker, M.   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy