Results 91 to 100 of about 7,468,732 (318)

Inference of Causal Networks Using a Topological Threshold

open access: yesIEEE Access
We propose a constraint-based algorithm, which automatically determines causal relevance thresholds, to infer causal networks from data. We call these topological thresholds.
Filipe Barroso   +2 more
doaj   +1 more source

Network Model Selection for Task-Focused Attributed Network Inference

open access: yes, 2017
Networks are models representing relationships between entities. Often these relationships are explicitly given, or we must learn a representation which generalizes and predicts observed behavior in underlying individual data (e.g. attributes or labels).
Berger-Wolf, Tanya Y.   +2 more
core   +1 more source

Inferring Centrality from Network Snapshots

open access: yesScientific Reports, 2017
AbstractThe topology and dynamics of a complex network shape its functionality. However, the topologies of many large-scale networks are either unavailable or incomplete. Without the explicit knowledge of network topology, we show how the data generated from the network dynamics can be utilised to infer the tempo centrality, which is proposed to ...
Haibin Shao   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Harnessing Unsupervised Ensemble Learning for Biomedical Applications: A Review of Methods and Advances

open access: yesMathematics
Advancements in data availability and computational techniques, including machine learning, have transformed the field of bioinformatics, enabling the robust analysis of complex, high-dimensional, and heterogeneous biomedical data.
Mehmet Eren Ahsen
doaj   +1 more source

Trace complexity of network inference [PDF]

open access: yesProceedings of the 19th ACM SIGKDD international conference on Knowledge discovery and data mining, 2013
25 pages, preliminary version appeared in Proceedings of the 19th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD 2013)
Bruno Abrahao   +3 more
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development

open access: yesFrontiers in Physiology, 2018
Avian ciliary ganglion (CG) development involves a transient execution phase of apoptosis controlling the final number of neurons, but the time-dependent molecular mechanisms for neuronal cell fate are largely unknown. To elucidate the molecular networks
Sophie Koszinowski   +11 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Differentiation of Residents’ Cultural Consumption Tendency and Consumption Recommendation System Based on Network Inference Algorithm

open access: yesFoundations of Computing and Decision Sciences
To address the issue of insufficient accuracy in consumer recommendation systems, a new biased network inference algorithm is proposed based on traditional network inference algorithms.
Lian Naiyu, Xu Hengzhe, Zhang Feiyang
doaj   +1 more source

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