Network meta-analysis is a popular way to combine results from several studies (usually randomized trials) comparing several treatments or interventions. It has usually been performed in a Bayesian setting, but recently it has become possible in a frequentist setting using multivariate meta-analysis and meta-regression, implemented in Stata with mvmeta.
Ian R White
exaly +8 more sources
Network meta-analysis and random walks [PDF]
Abstract Network meta-analysis (NMA) is a central tool for evidence synthesis in clinical research. The results of an NMA depend critically on the quality of evidence being pooled. In assessing the validity of an NMA, it is therefore important to know the proportion contributions of each direct treatment comparison to each network ...
Annabel L. Davies +4 more
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Incorporating dose effects in network meta-analysis. [PDF]
Systematic reviews with network meta-analysis that ignore potential dose effects could limit the applicability and validity of review findings. This article aims to help content experts (eg, clinicians), methodologists, and statisticians better ...
Watt, Jennifer A +7 more
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Network meta-analysis explained [PDF]
Healthcare decisions should be based on all relevant evidence.1 Usually, this is provided by randomised controlled trials (RCTs) comparing two or more interventions for a condition affecting a target population of interest, although other forms of evidence can be considered.1 2 When more than one study is available, meta-analysis can be used to combine
Dias, Sofia, Caldwell, Deborah
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Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials [PDF]
Objective: To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal anti-hypertensive exercise prescription practices. Design: Systematic review and
Wiles, J. +6 more
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Impact of tourniquet during knee arthroplasty: a bayesian network meta-analysis of peri-operative outcomes. [PDF]
INTRODUCTION: The role of tourniquet during knee arthroplasty is controversial. The present study compares various tourniquet protocols using a Bayesian network meta-analysis of peri-operative data.
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The statistical importance of a study for a network meta-analysis estimate [PDF]
BackgroundIn pairwise meta-analysis, the contribution of each study to the pooled estimate is given by its weight, which is based on the inverse variance of the estimate from that study.
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Inconsistent Results for Peto Odds Ratios in Multi-Arm Studies, Network Meta-Analysis and Indirect Comparisons. [PDF]
The Peto odds ratio is a well known effect measure in meta-analysis of binary outcomes. For pairwise comparisons, the Peto odds ratio estimator can be severely biased in the situation of unbalanced sample sizes in the two treatment groups or large ...
Efthimiou, Orestis +5 more
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Network meta‐analysis of multicomponent interventions [PDF]
AbstractIn network meta‐analysis (NMA), treatments can be complex interventions, for example, some treatments may be combinations of others or of common components. In standard NMA, all existing (single or combined) treatments are different nodes in the network.
Gerta Rücker +2 more
openaire +4 more sources
Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study. [PDF]
OBJECTIVE To examine whether the continuous updating of networks of prospectively planned randomised controlled trials (RCTs) ("living" network meta-analysis) provides strong evidence against the null hypothesis in comparative effectiveness of medical
Tricco, Andrea C +26 more
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