Results 31 to 40 of about 1,344,082 (280)

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

open access: yesJournal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah   +9 more
doaj   +1 more source

Effect of boswellia (Boswellia serrata L.) supplementation on glycemic markers and lipid profile in type 2 diabetic patients: a systematic review and meta-analysis

open access: yesFrontiers in Clinical Diabetes and Healthcare
BackgroundType 2 diabetes mellitus (T2DM) is a significant global health challenge whose prevalence is projected to increase alarmingly. Recently, due to better safety and fewer adverse effects, herbal medicines have been used to manage T2DM.
Mehdi Karimi   +7 more
doaj   +1 more source

Recent Research Trends in Meta-analysis

open access: yesAsian Nursing Research, 2017
The use of meta-analysis (MA), which is placed on top of the evidence hierarchy, in studies has been increasing exponentially. MA has three effect size families.
In-Soo Shin, PhD
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Training a Feed-forward Neural Network with Artificial Bee Colony Based Backpropagation Method

open access: yes, 2012
Back-propagation algorithm is one of the most widely used and popular techniques to optimize the feed forward neural network training. Nature inspired meta-heuristic algorithms also provide derivative-free solution to optimize complex problem. Artificial
Das, Achintya   +2 more
core   +1 more source

Treatments for gestational diabetes: a systematic review and meta-analysis [PDF]

open access: yes, 2017
Objective To investigate the effectiveness of different treatments for gestational diabetes mellitus (GDM). Design Systematic review, meta-analysis and network meta-analysis.
Ainuddin   +76 more
core   +6 more sources

Demystifying trial networks and network meta-analysis [PDF]

open access: yesBMJ, 2013
Networks of randomized clinical trials can be evaluated in the context of a network meta-analysis, a procedure that permits inferences into the comparative effectiveness of interventions that may or may not have been evaluated directly against each other.
Edward J, Mills   +2 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Sample size and power considerations in network meta-analysis

open access: yesSystematic Reviews, 2012
Background Network meta-analysis is becoming increasingly popular for establishing comparative effectiveness among multiple interventions for the same disease.
Thorlund Kristian, Mills Edward J
doaj   +1 more source

Antihypertensive Drug Use and the Risk of Depression: A Systematic Review and Network Meta-analysis

open access: yesFrontiers in Pharmacology, 2021
Background: Although numerous cohort studies have reported an association between antihypertensives use and depression, the exact effect of antihypertensives on depression remains unclear.Objective: To clarify the association between antihypertensives ...
Ying Li   +5 more
doaj   +1 more source

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