Results 51 to 60 of about 1,344,082 (280)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Network meta‐analysis

Journal of Oral Rehabilitation, 2017
Ton J. Cleophas, Aeilko H. Zwinderman
  +6 more sources

The First Fifty Years of Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID)

Acta Medica Iranica
Since the first successful hematopoietic stem cell transplantation (HSCT) in 1968 for severe combined immunodeficiency (SCID), clinical studies have commenced. However, there is a high heterogeneity across studies. This is a review of studies evaluating
Amene Saghazadeh, Andrew J. Cant, Nima Rezaei   +2 more
doaj   +1 more source

Evaluating the quality of evidence from a network meta-analysis.

PLoS ONE, 2014
Systematic reviews that collate data about the relative effects of multiple interventions via network meta-analysis are highly informative for decision-making purposes.
Georgia Salanti, Cinzia Del Giovane, Anna Chaimani, Deborah M Caldwell, Julian P T Higgins   +4 more
doaj   +1 more source

Network meta-analyses performed by contracting companies and commissioned by industry

Systematic Reviews, 2016
Background Industry commissions contracting companies to perform network meta-analysis for health technology assessment (HTA) and reimbursement submissions.
Ewoud Schuit, John PA Ioannidis
doaj   +1 more source

The best surgical treatment for cervical radiculopathy: A systematic review and network meta-analysis

Advanced Biomedical Research, 2023
A case with an inflamed or damaged nerve root in the cervical spine is defined as cervical radiculopathy.The purpose of the current study is to recognize the most effective surgical procedures in cervical radiculopathy subjects.
Afshin Almasi, Samira Jafari, Leila Solouki, Niloofar Darvishi   +3 more
doaj   +1 more source

A New Ensemble Learning Framework for 3D Biomedical Image Segmentation

, 2018
3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets.
Chen, Danny Z., Liang, Peixian, Wang, Chaoli, Yang, Lin, Zhang, Yizhe, Zhao, Zhuo, Zheng, Hao   +6 more
core   +1 more source

Evidence Synthesis for Decision Making 3:Heterogeneity Subgroups, Meta-Regression, Bias, and Bias-Adjustment [PDF]

, 2013
In meta-analysis, between-study heterogeneity indicates the presence of effect-modifiers and has implications for the interpretation of results in cost-effectiveness analysis and decision making.
Ades, A E, Dias, Sofia, Sutton, Alex J., Welton, Nicky J   +3 more
core   +2 more sources

Network Meta-Analysis of Onychomycosis Treatments [PDF]

Skin Appendage Disorders, 2015
<b><i>Background:</i></b> Many onychomycosis treatments have not been directly compared in head-to-head clinical trials. <b><i>Objective:</i></b> To determine the relative efficacy of onychomycosis treatments using network meta-analysis (NMA).
Aditya K. Gupta, Deanne Daigle, Kelly A. Foley   +2 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source