Results 31 to 40 of about 25,441 (255)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
PLoS ONE, 2020 In view of the strong nonlinear characteristics of the multi-packet transmission Aero-engine DCS with induced delay and random packet dropout, a neural network PID approach law sliding-mode controller using sliding window strategy and multi-kernel LS-SVM
Li Guangfu, Wang Xu, Ren Jia
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Network layer packet redundancy in optical packet switched networks
Optics Express, 2004 A crucial issue in optical packet switched (OPS) networks is packet losses at the network layer caused by contentions. This paper presents the network layer packet redundancy scheme (NLPRS), which is a novel approach to reduce the end-to-end data packet loss rate in OPS networks. By introducing redundancy packets in the OPS network, the NLPRS enables a
openaire +4 more sources
Proposed Hybrid-Encryption System for Multicast Network [PDF]
Engineering and Technology Journal, 2010 In this paper the proposed method based on two encrypted algorithms (Public key, and Block cipher) at the same time, it allowed a sender to encrypt the multicast packet and forward it into the packet network on the optimal distribution tree.
Mohammad Natiq Fadhil Ibraheem
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Design of the Ouroboros packet network
CoRR, 2020 The 5-layer TCP and 7-layer OSI models are taught as high-level frameworks in which the various protocols that are used in computer networks operate. These models provide valid insights in the organization of network functionalities and protocols; however, the difficulties to fit some crucial technologies within them hints that they don't provide a ...
Dimitri Staessens, Sander Vrijders
openaire +2 more sources