Results 51 to 60 of about 6,931,246 (294)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Research and Implication of Traffic Analyzing Technology in Mobile Packet Network Based on DPI Technology

open access: yesDianxin kexue, 2014
With the rapidly developing of mobile internet and the commercial use of 4G, monitoring the service traffic becomes more and more important to operators.
Yanrong Zhang   +3 more
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Research on Multi-Dimensional Packet Classification Algorithm

open access: yesDianxin kexue, 2014
With the increase of network services, multi-dimensional packet classification technology has become a core technology for network devices in the next generation internet.
Hanbing Liu, Yali Yang, Aina Hu
doaj   +2 more sources

PACKET TRANSPORT ON SCALE-FREE NETWORKS [PDF]

open access: yesAdvances in Complex Systems, 2002
We introduce a model of information packet transport on networks in which the packets are posted by a given rate and move in parallel according to a local search algorithm. By performing a number of simulations we investigate the major kinetic properties of the transport as a function of the network geometry, the packet input rate and the buffer size.
Tadic, B, Rodgers, GJ
openaire   +3 more sources

The eXpress data path: fast programmable packet processing in the operating system kernel

open access: yesConference on Emerging Network Experiment and Technology, 2018
Programmable packet processing is increasingly implemented using kernel bypass techniques, where a userspace application takes complete control of the networking hardware to avoid expensive context switches between kernel and userspace.
T. Høiland-Jørgensen   +6 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Dynamic homeostasis in packet switching networks [PDF]

open access: yesAdaptive Behavior, 2014
In this study, we investigate the adaptation and robustness of a packet switching network (PSN), the fundamental architecture of the Internet. We claim that the adaptation introduced by a transmission control protocol congestion control mechanism is interpretable as the self-organization of complex itinerant behavior among many quasi-attracting states.
Mizuki Oka   +2 more
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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