Results 41 to 50 of about 6,931,246 (294)
ACTIVE NETWORK SECURITY BASED RSA ALGORITHM
Journal of Engineering, 2009 The difficulty of building a secure network is due to the changing nature of the enterprise coupled with the increasing sophistication of the hacker threat, both from inside and outside of the network. Active networks enable individual user or groups of
Ahmed Freidoon Fadhil +1 more
doaj +1 more source
Anomalous Network Packet Detection Using Data Stream Mining
J. Information Security, 2011 In recent years, significant research has been devoted to the development of Intrusion Detection Systems (IDS) able to detect anomalous computer network traffic indicative of malicious activity.
Zachary Miller +2 more
semanticscholar +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Design of the Ouroboros packet network
CoRR, 2020 The 5-layer TCP and 7-layer OSI models are taught as high-level frameworks in which the various protocols that are used in computer networks operate. These models provide valid insights in the organization of network functionalities and protocols; however, the difficulties to fit some crucial technologies within them hints that they don't provide a ...
Dimitri Staessens, Sander Vrijders
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Proposed Hybrid-Encryption System for Multicast Network [PDF]
Engineering and Technology Journal, 2010 In this paper the proposed method based on two encrypted algorithms (Public key, and Block cipher) at the same time, it allowed a sender to encrypt the multicast packet and forward it into the packet network on the optimal distribution tree.
Mohammad Natiq Fadhil Ibraheem
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source