Results 251 to 260 of about 628,285 (376)

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Mechanistic Insights Into <i>Ganoderma Lucidum</i> for Diabetes Treatment via Network Pharmacology and Validation. [PDF]

Diabetes Metab Syndr Obes
Guo S, Yang L, Zhou J, Luo W, Nie B, Zhong X, Liu D, Kang X.   +7 more
europepmc   +1 more source

Pharmacological interventions for stress ulcer prophylaxis in critically ill patients: a mixed treatment comparison network meta-analysis and a recursive cumulative meta-analysis

, 2017
Kannan Sridharan, Gowri Sivaramakrishnan, Jerome Gnanaraj   +2 more
openalex   +2 more sources

Comparative Study Of Complex Network Community Structure Algorithms In network Pharmacology Analysis [PDF]

, 2018
Wangping Xiong, Xian Zhou, Bin Nie, Jianqiang Du   +3 more
openalex   +1 more source

Advancements in Biochar as a Sustainable Adsorbent for Water Pollution Mitigation

Advanced Science, EarlyView.
Biochar, obtained through pyrolysis of organic waste, serves as a sustainable solution for wastewater treatment due to its adaptability and low‐cost nature. This review comprehensively examines recent advancements in biochar production, functional modifications, and applications, highlighting the integration of machine learning and artificial ...
Devika Laishram, Su‐Bin Kim, Seul‐Yi Lee, Soo‐Jin Park   +3 more
wiley   +1 more source

Network pharmacology-based investigation of the pharmacological mechanisms of diosgenin in nonalcoholic steatohepatitis. [PDF]

Sci Rep
Gu P, Chen J, Xin J, Chen H, Zhang R, Chen D, Zhang Y, Shao S.   +7 more
europepmc   +1 more source

A Network Pharmacology Approach to Uncover the Potential Mechanism of Yinchensini Decoction

, 2018
Guoming Chen, Chuyao Huang, Yunyun Liu, Tengyu Chen, Ruilan Huang, Miaozhen Liang, Jie Zhang, Hua Xu   +7 more
openalex   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Lycopene's therapeutic mechanisms in epididymitis: a network pharmacology and experimental study. [PDF]

Transl Androl Urol
Zhan MW, Liu PF, Nie ZH, Zhan XX, Lou Q, Wang L, Wu JJ, Yu Y, Shang XJ.   +8 more
europepmc   +1 more source

A Multi‐Objective Molecular Generation Method Based on Pareto Algorithm and Monte Carlo Tree Search

Advanced Science, EarlyView.
Pareto Monte Carlo Tree Search Molecular Generation (PMMG), a molecular generation approach leveraging Monte Carlo Tree Search (MCTS) and Pareto algorithm, efficiently explores the Pareto front in high‐dimensional objective spaces for multi‐objective drug design.
Yifei Liu, Yiheng Zhu, Jike Wang, Renling Hu, Chao Shen, Wanglin Qu, Gaoang Wang, Qun Su, Yuchen Zhu, Yu Kang, Peichen Pan, Chang‐Yu Hsieh, Tingjun Hou   +12 more
wiley   +1 more source