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Network Pharmacology and Epilepsy
2016Fil: Talevi, Alan. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biologicas. Catedra de Quimica Medicinal; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas.
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Network Pharmacology: Exploring the Resources and Methodologies
Current Topics in Medicinal Chemistry, 2018Multi-target and combinatorial therapies have been focused for the past several decades. These approaches achieved considerable therapeutic efficacy by modulating the activities of the targets in complex diseases such as HIV-1 infection, cancer and diabetes disease.
Junaid, Muhammad +6 more
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Network Pharmacology: Reigning in Drug Attrition?
Current Drug Discovery Technologies, 2013In the process of drug development, there has been an exceptionally high attrition rate in oncological compounds entering late phases of testing. This has seen a concurrent reduction in approved NCEs (new chemical entities) reaching patients. Network pharmacology has become a valuable tool in understanding the fine details of drug-target interactions ...
Osama M, Alian +3 more
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The impact of network biology in pharmacology and toxicology
SAR and QSAR in Environmental Research, 2012With the need to investigate alternative approaches and emerging technologies in order to increase drug efficacy and reduce adverse drug effects, network biology offers a novel way of approaching drug discovery by considering the effect of a molecule and protein's function in a global physiological environment.
Panagiotou, G.; Taboureau, O.
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Standardized Drug and Pharmacological Class Network Construction [PDF]
, 2013 Dozens of drug terminologies and resources capture the drug and/or drug class information, ranging from their coverage and adequacy of representation. No transformative ways are available to link them together in a standard way, which hinders data integration and data representation for drug-related clinical and translational studies. In this paper, we
Qian Zhu 0003 +3 more
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Common Network Pharmacology Software
2021As a growing trend in current pharmacology research and an important medical application in network science research, network pharmacology has become an indispensable complement to traditional pharmacology research with the immense accumulation and integration of large-scale pharmacology and disease molecular network data.
Xuezhong Zhou, Ning Wang, Xing Zhai
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Editorial: Network pharmacology and AI
Journal of Ethnopharmacology, 2023Shao, Li +3 more
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Common Network Pharmacology Databases
2021Network pharmacology research is set against the background of vast biological databases and artificial intelligence. Traditional Chinese Medicine (TCM) involves ancient manuscripts, documents, and innumerable prescriptions belonging to various dynasties.
Haiyu Xu, Yanqiong Zhang, Feifei Guo
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Network‐based precision medicine and systems pharmacology
British Journal of PharmacologyThe growth in detailed multi‐omic profiling has created new opportunities to tailor clinical care and therapy to patient‐level variations in disease phenotype. However, efforts towards precision medicine and personalised therapeutics are hampered by limitations in identifying biologically relevant signals that ...
Arvind K, Pandey +2 more
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