Results 61 to 70 of about 419,821 (262)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Energy efficient routing protocols for wireless sensor networks: comparison and future directions

MATEC Web of Conferences, 2017
Wireless sensor network consists of nodes with limited resources. Hence, it is important to design protocols or algorithms which increases energy efficiency in order to improve the network lifetime.
Loganathan Murukesan, Sabapathy Thennarasan, Ghazali Nur Hafizah, Ahmad R Badlishah, Nasrun Osman Mohamed   +4 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Quick UDP Internet Connections and Transmission Control Protocol in unsafe networks: A comparative analysis

IET Smart Cities
Secure data transmission and efficient network performance are both key aspects of the modern Internet. Traditionally, Transport Layer Security (TLS)/Transmission Control Protocol (TCP) has been used for reliable and secure networking communications.
Andrew Simpson, Maitha Alshaali, Wanqing Tu, Muhammad Rizwan Asghar   +3 more
doaj   +1 more source

PREE: Heuristic builder for reverse engineering of network protocols in industrial control systems. [PDF]

Forensic Sci Int Digit Investig, 2023
Qasim SA, Jo W, Ahmed I.
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Pneumatic Vitreolysis with Perfluoropropane for Vitreomacular Traction with and without Macular Hole: DRCR Retina Network Protocols AG and AH. [PDF]

Ophthalmology, 2021
Chan CK, Mein CE, Glassman AR, Beaulieu WT, Calhoun CT, Jaffe GJ, Jampol LM, MacCumber MW, Maguire MG, Maturi RK, Salehi-Had H, Rofagha S, Sun JK, Martin DF, DRCR Retina Network.   +14 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

PAŽANGIŲJŲ MATAVIMŲ SISTEMŲ DIEGIMO PROBLEMATIKA DARBUOTOJŲ KOMPETENCIJŲ KONTEKSTE = PROBLEMS OF INTEGRATED MEASUREMENT SYSTEMS IN THE CONTEXT OF EMPLOYEES' COMPETENCES

Taikomieji tyrimai studijose ir praktikoje, 2018
The adoption of energy efficiency measures is shifting the building installation industry towards green technologies, such as smart metering and home automation, bringing significant changes on workplace requirements and training.
Gediminas Bačkys, Renata Černeckienė, Birutė Dalmantienė   +2 more
doaj