Results 81 to 90 of about 1,278,074 (287)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cooja TimeLine: A Power Visualizer for Sensor Network Simulation [PDF]
, 2010 Power consumption is one of the most important factors in wireless sensor network research, but most simulators do not provide support for visualizing the power consumption of an entire sensor network.
Dunkels, Adam +2 more
core +1 more source
Distributed Weight Selection in Consensus Protocols by Schatten Norm Minimization
, 2014 In average consensus protocols, nodes in a network perform an iterative weighted average of their estimates and those of their neighbors. The protocol converges to the average of initial estimates of all nodes found in the network.
Avrachenkov, Konstantin +2 more
core +3 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Energy efficient routing protocols for wireless sensor networks: comparison and future directions
MATEC Web of Conferences, 2017 Wireless sensor network consists of nodes with limited resources. Hence, it is important to design protocols or algorithms which increases energy efficiency in order to improve the network lifetime.
Loganathan Murukesan +4 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
IET Smart CitiesSecure data transmission and efficient network performance are both key aspects of the modern Internet. Traditionally, Transport Layer Security (TLS)/Transmission Control Protocol (TCP) has been used for reliable and secure networking communications.
Andrew Simpson +3 more
doaj +1 more source
PREE: Heuristic builder for reverse engineering of network protocols in industrial control systems. [PDF]
Forensic Sci Int Digit Investig, 2023 Qasim SA, Jo W, Ahmed I.
europepmc +1 more source
OLIMPO, An Ad-Hoc Wireless Sensor Network Simulator for Public Utilities Applications [PDF]
, 2005 This paper introduces OLIMPO, an useful simulation tool for researchers who are developing wireless sensor communication protocols. OLIMPO is a discreteevent simulator design to be easily recon gured by the user, providing a way to design, develop ...
Barbancho Concejero, Antonio +4 more
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source