Results 101 to 110 of about 574,210 (309)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Exploiting Centrality Information with Graph Convolutions for Network Representation Learning
, 2019 Network embedding has been proven effective to learn low-dimensional vector representations for network vertices, and recently received a tremendous amount of research attention.
Tong Chen +11 more
core +1 more source
Network Representation Learning
大数据, 2015 Along with the constant growth of massive online social networks such as Facebook,Twitter,Weixin and Weibo,a tremendous amount of network data sets are generated.How to represent the data is an important aspect when we apply machine learning techniques ...
Weizheng Chen, Yan Zhang, Xiaoming Li
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Knowledge Representation and WordNets [PDF]
Knowledge itself is a representation of “real facts”. Knowledge is a logical model that presents facts from “the real world” witch can be expressed in a formal language. Representation means the construction of a model of some part of reality. Knowledge
Alexandra Gabriela Tudorache
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Coalitional Games via Network Flows
, 2013 We introduce a new representation scheme for coalitional games, called coalition-flow networks (CF-NETs), where the formation of effective coalitions in a task-based setting is reduced to the problem of directing flow through a network.
Polukarov, Maria +7 more
core
Network representation of higher-order interactions based on information dynamics
Many complex systems in science and engineering are modeled as networks whose nodes and links depict the temporal evolution of each system unit and the dynamic interaction between pairs of units, which are assessed respectively using measures of auto ...
Stramaglia, Sebastiano +5 more
core +1 more source
LinkedDataLens: Linked Data as a Network of Networks
, 2011 With billions of assertions and counting, the Web of Data represents the largest multi-contributor interlinked knowledge base that ever existed. We present a novel framework for analyzing and using the Web of Data based on extracting and analyzing ...
Corcho, Ó +3 more
core +1 more source
NodeVector: A Novel Network Node Vectorization with Graph Analysis and Deep Learning
Applied SciencesNetwork node embedding captures structural and relational information of nodes in the network and allows for us to use machine learning algorithms for various prediction tasks on network data that have an inherently complex and disordered structure ...
Volkan Altuntas
doaj +1 more source