Results 61 to 70 of about 574,210 (309)

Dynamic Community Detection Method of a Social Network Based on Node Embedding Representation

open access: yesMathematics, 2022
The node embedding method enables network structure feature learning and representation for social network community detection. However, the traditional node embedding method only focuses on a node’s individual feature representation and ignores the ...
Bo Zhang   +6 more
doaj   +1 more source

Ensemble Neural Representation Networks

open access: yes, 2022
Abstract Implicit Neural Representation (INR) has recently attracted considerable attention for continuous characterization of various types of signals. The existing INR techniques require lengthy training processes and high-performance computing.
Milad Soltany Kadarvish   +6 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural representation learning for network alignment with self-supervised anchor links

open access: yes, 2020
Network alignment, the problem of identifying similar nodes across networks, is an emerging research topic due to its ubiquitous applications in many data domains such as social-network reconciliation and protein-network analysis.
Huynh, Thanh Trung   +6 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

OFFER: A Motif Dimensional Framework for Network Representation Learning

open access: yes, 2020
Aiming at better representing multivariate relationships, this paper investigates a motif dimensional framework for higher-order graph learning. The graph learning effectiveness can be improved through OFFER.
Lee, Ivan   +14 more
core   +1 more source

Explicit Object Representation by Sparse Neural Codes [PDF]

open access: yes, 2008
Neurons have been identified in the human medial temporal lobe (MTL) that display a strong selectivity for only a few stimuli (such as familiar individuals or landmark buildings) out of perhaps 100 presented to the test subject.
Waydo, Stephen J.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy