Results 91 to 100 of about 878 (261)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A New Key Delivery Method in Wireless Network
The development of networking technologies and the increase of digital devices have made multimedia transmission quick and easy. However, digital data transmission over open communication channels has introduced a number of security implications, such as
Çağatay Ay
doaj
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
ISEM:image steganography enhancement model based on generative multi-adversarial network
Image steganography techniques were typically categorized into symmetric and asymmetric types based on whether the embedding costs of +1 and -1 within the same embedding unit were equal.
ZHOU Saixing, YE Miaoxin, LUO Weiqi
doaj
Reversible Image Steganography Scheme Based on a U-Net Structure
Traditional steganography methods often hide secret data by establishing a mapping relationship between secret data and a cover image or directly in a noisy area, but has a low embedding capacity.
Xintao Duan +5 more
doaj +1 more source
StegBlocks: ensuring perfect undetectability of network steganography
6 pages, 1 figure, Accepted to Fourth International Workshop on Cyber Crime (IWCC 2015), co-located with 10th International Conference on Availability, Reliability and Security (ARES 2015), Toulouse, France, 24-28 August ...
Wojciech Fraczek, Krzysztof Szczypiorski
openaire +2 more sources
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

