Results 81 to 90 of about 8,587 (278)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Proposed Algorithm for Steganography
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 Steganography is an important class of security which is widely used in computer and network security nowadays. In this research, a new proposed algorithm was introduced with a new concept of dealing with steganography as an algorithmic secret key ...
A.O. Ibadi, O. Z. Akif
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
AUDIO CRYPTANALYSIS- AN APPLICATION OF SYMMETRIC KEY CRYPTOGRAPHY AND AUDIO STEGANOGRAPHY
ICTACT Journal on Communication Technology, 2016 In the recent trend of network and technology, “Cryptography” and “Steganography” have emerged out as the essential elements of providing network security. Although Cryptography plays a major role in the fabrication and modification of the secret message
Smita Paira, Sourabh Chandra
doaj
Adaptive Image Steganography Algorithm Based on Deep Reinforcement Learning [PDF]
Jisuanji gongchengThis study proposes an Adaptive Image Steganography Algorithm based on Deep Reinforcement Learning (AISA-DRL) to realize a balance among lightweight steganography, optimal embedding positioning, and high hidden outputs. A lightweight secure steganography
Qing QIAN, Yong LONG, Zhongyuan JIANG, Chunhong DUAN, Hong WANG
doaj +1 more source
Steganography Defense Network Based on Simulation of Steganography Information Distribution
International Journal of Intelligent SystemsIn order to block the spread of illegal stego‐image and reduce the erasing traces of steganography attacks on images, this paper proposes a steganography attack network based on simulation of steganography information distribution. First, a strategy of simulating steganography noise was adopted, and the distribution of steganography noise was learned ...
Jinjin Liu +4 more
openaire +1 more source