Results 51 to 60 of about 577,646 (335)

Sufficient Conditions for Fast Switching Synchronization in Time Varying Network Topologies

, 2005
In previous work, empirical evidence indicated that a time-varying network could propagate sufficient information to allow synchronization of the sometimes coupled oscillators, despite an instantaneously disconnected topology.
Afra movich V., D. Gray Roberson, Daniel J. Stilwell, Erik M. Bollt, Glass Leon, Guevara M. R., Jost J., Netoff T. I., Sansone G.   +8 more
core   +2 more sources

Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology [PDF]

, 2010
Background In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centrality-lethality rule", which indicates that the topological placement of a protein in
Leong, Hon Wai, Nesvizhskii, Alexey I., Ng, Hoong Kee, Ning, Kang, Srihari, Sriganesh   +4 more
core   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Pruning to Increase Taylor Dispersion in Physarum polycephalum Networks

, 2016
How do the topology and geometry of a tubular network affect the spread of particles within fluid flows? We investigate patterns of effective dispersion in the hierarchical, biological transport network formed by Physarum polycephalum.
Alim, Karen, Andrew, Natalie, Brenner, Michael P., Marbach, Sophie, Pringle, Anne   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Topological Planning of Communication Networks

Journal of information and organizational sciences, 2002
In this paper, we concentrate on topological planning process of large-scale communication networks such as those used by telecom operators. Such networks are usually spread over large geographical area, and finding an optimal topology is very important part of the planning process.
Kos, Mladen, Mikac, Matija, Mikac, Domagoj   +2 more
openaire   +5 more sources

A Multilevel Approach to Topology-Aware Collective Operations in Computational Grids [PDF]

, 2002
The efficient implementation of collective communiction operations has received much attention. Initial efforts produced "optimal" trees based on network communication models that assumed equal point-to-point latencies between any two processes.
de Supinski, B., Foster, I., Gropp, W., Karonis, N. T., Lusk, E.   +4 more
core  

Graph Annotations in Modeling Complex Network Topologies

, 2009
The coarsest approximation of the structure of a complex network, such as the Internet, is a simple undirected unweighted graph. This approximation, however, loses too much detail.
Amin Vahdat, Chang H., Dimitropoulos X., Dimitropoulos X., Dmitri Krioukov, Erdős P., Gao L., George Riley, Gkantsidis C., Lakhina A., Medina A., Nelson R. B., Palmer C., Söderberg B., Xenofontas Dimitropoulos, Zegura E. W.   +15 more
core   +1 more source