Results 171 to 180 of about 116,230 (268)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Exploring the Barriers Faced by Medical Students and the Impact of Their Involvement in a Widening Participation Charity. [PDF]

Adv Med Educ Pract
James E, Haque E.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Assessment of Perceived Scientific and Social Benefits and Satisfaction Levels among Participants of a Critical Care Academic Conference: A Survey-based Study. [PDF]

Ann Card Anaesth
Ghatak T, Ramamoorthy SV, Mani UA, Lohia A, Mishra P, Singh RK.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Workplace Upward Networking Between Affective Leadership and Voice Behavior. [PDF]

J Nurs Adm
Zhu Y, Qian L, Qian D, Xu S, Yan L, Yang J, Zhou Q.   +6 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Widening participation in the International League Against Epilepsy: Looking to the future. [PDF]

Epilepsia Open
Cross JH, Coleman L, Oritz S, Ivaniuk A, Nome CG, Roza E, Shafer PO, von Gaudecker J, Ryan C, Brinkmann BH, Neuray C, Welty T, Wiebe S, Guekht A.   +13 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Public views, patterns, and impacts of social networking site use for medicine-related information in Saudi Arabia: A cross-sectional study. [PDF]

J Public Health Res
Alhomoud F, Alhomoud FK, Al Muslim A, Altheeb S, Al Subait R, Alsadah H, Alsultan B, Alamer M, Alqurain AA, Alfageh B, Almoghirah H.   +10 more
europepmc   +1 more source