Results 181 to 190 of about 392,800 (301)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Chemical Profiling and Anti-Inflammatory Mechanisms of <i>Heracleum millefolium Diels</i> Revealed by Molecular Networking, Network Pharmacology, and Cellular Validation. [PDF]

Metabolites
Zhu G, Yin X, Dunzhu C, Zhou X, Shao M, Yuan E, Yan Z, Xie X.   +7 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Intelligent Matching Algorithm with Density-Based Clustering for UAV Swarm Networking. [PDF]

Sensors (Basel)
Kong L, Guo D, Xu J, Wang F, Wu J, Xin X.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Effectiveness of peer-delivered Problem Management Plus for Immigrants (PMP-I) in reducing stress, anxiety, and depressive symptoms among Bhutanese adults resettled in Massachusetts, United States: a pilot randomized controlled trial. [PDF]

Epidemiol Psychiatr Sci
Poudel-Tandukar K, Laws H, Martell CR, Rai S, Ramdam R, Meyer JS, Bertone-Johnson ER, Jacelon CS, Hollon SD.   +8 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Geometry-Based Neural-Network Prediction of Electron Localization Function Topology in Dense Hydrogen. [PDF]

Chemistry
Wang X, Marqués M, Gómez S, Serratosa F, Zurek E, Contreras-García J.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Immediate and Longitudinal Outcomes of a National Hands-On Basic Research Course in Rhinology. [PDF]

Laryngoscope Investig Otolaryngol
Kumai T, Takizawa Y, Suzaki I, Kono M, Maruyama Y, Yun Y, Imoto Y, Kanda A, Okano M, Takeno S.   +9 more
europepmc   +1 more source