Results 191 to 197 of about 16,068 (197)

Efficient whole-cell biocatalyst for Neu5Ac production by manipulating synthetic, degradation and transmembrane pathways

Biotechnology Letters, 2016
To develop a strategy for producing N-acetyl-D-neuraminic acid (Neu5Ac), which is often synthesized from exogenous N-acetylglucosamine (GlcNAc) and pyruvate, but without using pyruvate.An efficient three-module whole-cell biocatalyst strategy for Neu5Ac production by utilizing intracellular phosphoenolpyruvate was established.
Deqiang, Zhu, Xiaobei, Zhan, Jianrong, Wu, Minjie, Gao, Zhongsheng, Zhao   +4 more
openaire   +2 more sources

Unique Self‐Anhydride Formation in the Degradation of Cytidine‐5′‐monophosphosialic Acid (CMP‐Neu5Ac) and Cytidine‐5′‐diphosphosialic Acid (CDP‐Neu5Ac) and its Application in CMP‐sialic Acid Analogue Synthesis

Chemistry – A European Journal, 2011
AbstractSialyloligosaccharides are synthesised by various glycosyltransferases and sugar nucleotides. All of these nucleotides are diphosphate compounds except for cytidine‐5′‐monophosphosialic acid (CMP‐Neu5Ac). To obtain an insight into why cytidine‐5′‐diphosphosialic acid (CDP‐Neu5Ac) has not been used for the sialyltransferase reaction and why it ...
Yasuhiro, Kajihara, Sachiko, Nishigaki, Daisuke, Hanzawa, Go, Nakanishi, Ryo, Okamoto, Naoki, Yamamoto   +5 more
openaire   +2 more sources

Synthesis of a novel CMP-Neu5Ac analogue: CMP- [α-Neu5Ac- (2 → 8)-Neu5Ac]

Carbohydrate Research, 1994
Y, Kajihara, K, Koseki, T, Ebata, H, Kodama, H, Matsushita, H, Hashimoto   +5 more
openaire   +2 more sources

Synthesis of phosphonic acid analogues of sialic acid Neu5Ac

Chemical Communications, 1996
Tak-Hang Chan, Yan-Chao Xin
openaire   +1 more source

CMP-Neu5Ac-synthesis: why in the cell nucleus?

2003
Gerardy-Schahn, R., Tiralongo, J., Krapp, S., Weinhold, B., Ritz, V., Jacob, U., Munster, A.   +6 more
openaire   +1 more source

High-level expression of recombinant Neisseria CMP-Neu5Ac synthetase and its use in the gram-scale synthesis of CMP-Neu5Ac: Prot.Expr.Pur.

2002
Karwaski, M., Wakarchuk, W., Gilbert, M.
openaire   +1 more source

Process development for the biocatalytic synthesis of CMP-Neu5Ac

2023
openaire   +1 more source