Neural cell adhesion molecule regulates chondrocyte hypertrophy in chondrogenic differentiation and experimental osteoarthritis [PDF]
Stem Cells Translational Medicine, 2020 Chondrocyte hypertrophy‐like change is an important pathological process of osteoarthritis (OA), but the mechanism remains largely unknown. Neural cell adhesion molecule (NCAM) is highly expressed and involved in the chondrocyte differentiation of ...
Bin‐Feng Cheng +9 more
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Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice [PDF]
Brain and Behavior, 2022 Background and purpose Intracerebral hemorrhage (ICH) is a subtype of stroke and results in neurological deficits in patients without any effective treatments. Artemisinin (ART), a well‐known antimalarial Chinese medicine, exerts multiple essential roles
Jianjiang Wang, Jie Yin, Xi Zheng
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Neuronal cell adhesion molecule regulating neural systems underlying addiction
Neuropsychopharmacology Reports, 2019 Aims The human NRCAM gene is associated with polysubstance use. Nrcam knockout mice do not acquire a preference for addictive substances. We aimed to elucidate the role of Nrcam in specific neural circuits underlying congenital preference for substances ...
Hiroki Ishiguro +5 more
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p75 and neural cell adhesion molecule 1 can identify pathologic Schwann cells in peripheral neuropathies [PDF]
Annals of Clinical and Translational Neurology, 2019 Objective Myelinated Schwann cells (SCs) in adult peripheral nerves dedifferentiate into immature cells in demyelinating neuropathies and Wallerian degeneration.
Young Hee Kim +15 more
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Alterations in the polysialylated neural cell adhesion molecule and retinal ganglion cell density in mice with diabetic retinopathy [PDF]
International Journal of Ophthalmology, 2018 AIM: To investigate the impact of polysialylated neural cell adhesion molecule (PSA-NCAM) on the survival of retinal ganglion cells (RGCs) in the experimentally induced diabetes in mice. METHODS: Diabetes was induced in 2.5 months old Swiss Webster mice
Natalia Lobanovskaya +3 more
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The ubiquitous neural cell adhesion molecule (N-CAM). [PDF]
Ann Med Surg (Lond), 2014 Adhesive interactions are important for cell trafficking, differentiation, function and tissue differentiation. Neural cell adhesion molecule (NCAM) is involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes.
Weledji EP, Assob JC.
europepmc +3 more sources
The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. [PDF]
PLoS ONE, 2015 Despite its multi-faceted role in neurodegenerative diseases, the physiological function of the prion protein (PrP) has remained elusive. On the basis of its evolutionary relationship to ZIP metal ion transporters, we considered that PrP may contribute ...
Mohadeseh Mehrabian +5 more
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Promotion of cell migration by neural cell adhesion molecule (NCAM) is enhanced by PSA in a polysialyltransferase-specific manner. [PDF]
PLoS ONE, 2015 Neural cell adhesion molecule 140 (NCAM-140) is a glycoprotein and always highly polysialylated in cancer. Functions of polysialic acid (PSA) that binds to N-glycan termini on NCAM remain unclear.
Feng Guan, Xin Wang, Fa He
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ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation. [PDF]
Mol Cell Biol, 2016 The neural cell adhesion molecule (NCAM) mediates cell-cell and cell-matrix adhesion. It is broadly expressed in the nervous system and regulates neurite outgrowth, synaptogenesis, and synaptic plasticity. Previous in vitro studies revealed that palmitoylation of NCAM is required for fibroblast growth factor 2 (FGF2)-stimulated neurite outgrowth and ...
Lievens PM +11 more
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Neural Cells adhesion Molecule NCAM in neural and endocrine cells [PDF]
, 1991 Langley, K., Gratzl, Manfred
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