Promotion of spinal cord regeneration by neural stem cell-secreted trimerized cell adhesion molecule L1. [PDF]
The L1 cell adhesion molecule promotes neurite outgrowth and neuronal survival in homophilic and heterophilic interactions and enhances neurite outgrowth and neuronal survival homophilically, i.e. by self binding.
Xiaowen He +6 more
doaj +1 more source
Regulation of Extrasynaptic Glutamatergic Signaling by Polysialylated NCAM in Health and Disease
The neural cell adhesion molecule NCAM is known to mediate cell–to–cell and cell–to–extracellular matrix (ECM) adhesion via homophilic and heterophilic interactions.
Alexander Dityatev
doaj +1 more source
Cultured microvascular endothelial cells derived from the bovine corpus luteum possess NCAM-140 [PDF]
Previously, five phenotypically different, stable types of microvascular endothelial cells (MVE) were isolated from the bovine corpus and cultured successfully. We found that three out of these five types of MVE express the neural cell adhesion molecule (
Caney +11 more
core +1 more source
P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1
Our recent transcriptome profiling studies suggest that presenilin 1 (PS1) regulates expression of neural cell adhesion molecule (Ncam1) through p75 neurotrophin receptor.
Zeljka Korade Mirnics +7 more
doaj +1 more source
Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E +4 more
core +1 more source
The expression of nerve cell adhesion molecule L1 in the neuronal growth cone of the central nervous system is strongly associated with the direction of growth of the axon, but its role in the regeneration of the peripheral nerve is still unknown.
Qian-ru He +7 more
doaj +1 more source
Potential Therapeutic Applications of N-Cadherin Antagonists and Agonists
This review focuses on the cell adhesion molecule (CAM), known as neural (N)-cadherin (CDH2). The molecular basis of N-cadherin-mediated intercellular adhesion is discussed, as well as the intracellular signaling pathways regulated by this CAM.
Orest W. Blaschuk
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Neural cell adhesion molecule expression on renal interstitial cells [PDF]
At early stages of kidney development, the neural cell adhesion molecule (NCAM) is highly expressed on cells of the metanephrogenic mesenchyme. During maturation of the fetal kidney, NCAM gradually disappears. So far, it has been widely accepted that NCAM in the adult kidney is only expressed by nerves, and not by other cell types.NCAM expression was ...
Markovic-Lipkovski, Jasmina +7 more
openaire +3 more sources
GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function
Summary: During embryonic development of the cerebellum, Purkinje cells (PCs) migrate away from the ventricular zone to form the PC plate. The mechanisms that regulate PC migration are incompletely understood.
Maria Christina Sergaki +1 more
doaj +1 more source
Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion molecules play important functions in the developing nervous system by regulating ...
Vladimir eSytnyk, Iryna eLeshchyns'Ka
doaj +1 more source

