Promotion of spinal cord regeneration by neural stem cell-secreted trimerized cell adhesion molecule L1. [PDF]
PLoS ONE, 2012 The L1 cell adhesion molecule promotes neurite outgrowth and neuronal survival in homophilic and heterophilic interactions and enhances neurite outgrowth and neuronal survival homophilically, i.e. by self binding.
Xiaowen He +6 more
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Regulation of Extrasynaptic Glutamatergic Signaling by Polysialylated NCAM in Health and Disease
Biology and Life Sciences Forum, 2023 The neural cell adhesion molecule NCAM is known to mediate cell–to–cell and cell–to–extracellular matrix (ECM) adhesion via homophilic and heterophilic interactions.
Alexander Dityatev
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Cultured microvascular endothelial cells derived from the bovine corpus luteum possess NCAM-140 [PDF]
, 1992 Previously, five phenotypically different, stable types of microvascular endothelial cells (MVE) were isolated from the bovine corpus and cultured successfully. We found that three out of these five types of MVE express the neural cell adhesion molecule (
Caney +11 more
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Potential Therapeutic Applications of N-Cadherin Antagonists and Agonists
Frontiers in Cell and Developmental Biology, 2022 This review focuses on the cell adhesion molecule (CAM), known as neural (N)-cadherin (CDH2). The molecular basis of N-cadherin-mediated intercellular adhesion is discussed, as well as the intracellular signaling pathways regulated by this CAM.
Orest W. Blaschuk
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Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
, 2016 During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo +5 more
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Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]
, 2017 The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E +4 more
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The Neural Cell Adhesion Molecule Is a Receptor for Rabies Virus [PDF]
Journal of Virology, 1998 ABSTRACT Previous reports strongly suggest that, in addition to the nicotinic acetylcholine receptor, rabies virus can use other, as-yet-unidentified receptors. We found that laboratory cell lines susceptible to rabies virus infection express the neural cell adhesion molecule (NCAM) (CD56) on their surface, whereas resistant cells do not ...
Thoulouze, Marie-Isabelle +5 more
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Neuronal cell adhesion molecule regulating neural systems underlying addiction
Neuropsychopharmacology Reports, 2019 Aims The human NRCAM gene is associated with polysubstance use. Nrcam knockout mice do not acquire a preference for addictive substances. We aimed to elucidate the role of Nrcam in specific neural circuits underlying congenital preference for substances ...
Hiroki Ishiguro +5 more
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Neural Cell Adhesion Molecule (NCAM) and Myoblast Fusion [PDF]
Developmental Biology, 2000 Considerable evidence points to an involvement of neural cell adhesion molecule (NCAM) in myoblast fusion. Changes in the level of NCAM expression, isoform specificity, and localization in muscle cells and tissues correspond to key morphogenetic events during muscle differentiation and repair. Furthermore, anti-NCAM antibodies have been shown by others
William A. Mohler +2 more
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Neural Regeneration Research, 2016 The expression of nerve cell adhesion molecule L1 in the neuronal growth cone of the central nervous system is strongly associated with the direction of growth of the axon, but its role in the regeneration of the peripheral nerve is still unknown.
Qian-ru He +7 more
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