Results 71 to 80 of about 131,590 (354)

Designing stem cell niches for differentiation and self-renewal [PDF]

, 2018
Mesenchymal stem cells, characterized by their ability to differentiate into skeletal tissues and self-renew, hold great promise for both regenerative medicine and novel therapeutic discovery. However, their regenerative capacity is retained only when in
Dalby, Matthew J., Donnelly, Hannah, Salmeron-Sanchez, Manuel   +2 more
core   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Mathematical models for somite formation [PDF]

, 2007
Somitogenesis is the process of division of the anterior–posterior vertebrate embryonic axis into similar morphological units known as somites. These segments generate the prepattern which guides formation of the vertebrae, ribs and other associated ...
Armstrong, Aulehla, Aulehla, Aulehla, Baker, Baker, Baker, Chernoff, Collier, Cooke, Cooke, Cooke, Dale, Dale, Dale, del Barco Barrantes, Dequéant, Diez del Corral, Diez del Corral, Diez del Corral, Drake, Duband, Dubrulle, Dubrulle, Dubrulle, Dubrulle, Duguay, Foty, Galli, Giudicelli, Goldbeter, Gossler, Grima, Haraguichi, Hirata, Horikawa, Ishikawa, Jiang, Jiang, Kalcheim, Kulesa, Lewis, Maroto, McGrew, McGrew, McInerney, Meier, Molotkova, Monk, Moreno, Morimoto, Packard, Packard, Palmeirim, Pourquié, Pourquié, Pourquié, Pourquié, Pourquié, Pourquié, Primmett, Primmett, Rida, Saga, Schnell, Schnell, Schnell, Stockdale, Tabin, Takahashi, Takashi, Tam, Turner   +72 more
core   +3 more sources

GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function

Cell Reports, 2017
Summary: During embryonic development of the cerebellum, Purkinje cells (PCs) migrate away from the ventricular zone to form the PC plate. The mechanisms that regulate PC migration are incompletely understood.
Maria Christina Sergaki, Carlos F. Ibáñez   +1 more
doaj  

Avian neural crest cell attachment to laminin: involvement of divalent cation dependent and independent integrins [PDF]

, 1991
The mechanisms of neural crest cell interaction with laminin were explored using a quantitative cell attachment assay. With increasing substratum concentrations, an increasing percentage of neural crest cells adhere to laminin.
Bronner-Fraser, Marianne, Lallier, Thomas   +1 more
core  

Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11. [PDF]

, 2012
The zebrafish adult pigment pattern has emerged as a useful model for understanding the development and evolution of adult form as well as pattern-forming mechanisms more generally.
Eom, Dae Seok, Gordon, Tiffany N, Inoue, Shinya, Kondo, Shigeru, Parichy, David M, Patterson, Larissa B, Slingwine, Rebecca, Watanabe, Masakatsu   +7 more
core   +2 more sources

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis

International Journal of Cell Biology, 2012
Metastasis is a major clinical problem and results in a poor prognosis for most cancers. The metastatic pathway describes the process by which cancer cells give rise to a metastatic lesion in a new tissue or organ.
Chee Wai Wong, Danielle E. Dye, Deirdre R. Coombe   +2 more
doaj   +1 more source

Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila.

PLoS Genetics, 2022
How cell to cell interactions control local tissue growth to attain a species-specific organ size is a central question in developmental biology. The Drosophila Neural Cell Adhesion Molecule, Fasciclin 2, is expressed during the development of neural and
Emma Velasquez, Jose A Gomez-Sanchez, Emmanuelle Donier, Carmen Grijota-Martinez, Hugo Cabedo, Luis Garcia-Alonso   +5 more
doaj   +1 more source

The Many Hats of Sonic Hedgehog Signaling in Nervous System Development and Disease. [PDF]

, 2016
Sonic hedgehog (Shh) signaling occurs concurrently with the many processes that constitute nervous system development. Although Shh is mostly known for its proliferative and morphogenic action through its effects on neural stem cells and progenitors, it ...
Belgacem, Yesser H, Borodinsky, Laura N, Hamilton, Andrew M, Shim, Sangwoo, Spencer, Kira A   +4 more
core   +2 more sources