Results 71 to 80 of about 251,945 (399)

Human basement membrane heparan sulfate proteoglycan core protein: a 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor

open access: yesJournal of Cell Biology, 1992
The primary structure of the large human basement membrane heparan sulfate proteoglycan (HSPG) core protein was determined from cDNA clones. The cDNA sequence codes for a 467-kD protein with a 21-residue signal peptide.
P. Kallunki, K. Tryggvason
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The ubiquitous neural cell adhesion molecule (N-CAM)

open access: yesAnnals of Medicine & Surgery, 2014
Adhesive interactions are important for cell trafficking, differentiation, function and tissue differentiation. Neural cell adhesion molecule (NCAM) is involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes.
Jules Clement Nguedia Assob   +1 more
openaire   +3 more sources

Rapid axonal transport of the neural cell adhesion molecule [PDF]

open access: yesThe Journal of Neuroscience, 1986
The neural cell adhesion molecule (NCAM) is a cell-surface glycoprotein that mediates cell-cell interactions in the nervous system during development. In the present study, we demonstrate that NCAM is axonally transported in 3-d-old chick retinal ganglion cells and that it travels within the fast component of axonal transport (FC).
J. A. Garner   +2 more
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Cadherin-mediated cell adhesion is critical for the closing of the mouse optic fissure. [PDF]

open access: yesPLoS ONE, 2012
Coloboma is a congenital disease that contributes significantly to childhood blindness. It results from the failure in closing the optic fissure, a transient opening on the ventral side of the developing eye. Although human and mouse genetic studies have
Shuyi Chen   +3 more
doaj   +1 more source

Solving the binding problem: cellular adhesive molecules and their control of the cortical quantum entangled network [PDF]

open access: yes, 2003
Quantum entanglement is shown to be the only acceptable physical solution to the binding problem. The biological basis of interneuronal entanglement is described in the frames of the beta-neurexin-neuroligin model developed by Georgiev (2002) and is ...
Georgiev, Danko
core  

Isolation, characterization, and substrate properties of the external limiting membrane from the avian embryonic optic tectum [PDF]

open access: yes, 1990
The external limiting membrane of the avian embryonic optic tectum is isolated by mechanically separating the neuronal mesencephalon from the overlying mesenchymal tissue.
Adler   +58 more
core   +1 more source

The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth

open access: yesJournal of Cell Biology, 1994
We have previously shown that aggregation of microbeads coated with N- CAM and Ng-CAM is inhibited by incubation with soluble neurocan, a chondroitin sulfate proteoglycan of brain, suggesting that neurocan binds to these cell adhesion molecules (Grumet ...
D. Friedlander   +5 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

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