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Mammalian neural crest and neural crest derivatives

Annals of Anatomy - Anatomischer Anzeiger, 1993
In the mammalian embryonic trunk, neural crest cells emigrate from the closed neural tube in a cranio-caudal sequences and appear to have similar migration pathways and derivatives to those of avian embryos. In the cranial region, however, there are mammalian-specific features, which are related to the mammalian-specific pattern of cranial neurulation.
G, Morriss-Kay, E, Ruberte, Y, Fukiishi
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Wnts and the neural crest

Anatomy and Embryology, 2005
The neural crest is a multipotent tissue that originates between the neural epithelium and non-neural ectoderm, which can develop into numerous cell types, including neurons, glia, pigment cells, smooth muscle, cartilage and bone. Work in a variety of animal models has shown that a number of signalling factors are necessary for the induction ...
Corina, Schmidt, Ketan, Patel
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Multipotentiality of the neural crest

Current Opinion in Genetics & Development, 2003
Multiple neural and non-neural cell types arise from the neural crest (NC) in vertebrate embryos. Recent work has provided evidence for multipotent stem cells and intermediate precursors in the early NC cell population as well as in various NC derivatives in embryos and even in adult.
Nicole M, Le Douarin, Elisabeth, Dupin
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Cardiac neural crest

Seminars in Cell & Developmental Biology, 2005
Neural crest cells (NCCs) contribute to many organs and tissues during embryonic development. Amongst these, the cardiovascular system represents a fascinating example. In this review, recent advances in our understanding of the developmental biology and molecular genetics regulating cardiac NCC maturation will be summarized.
Jason Z, Stoller, Jonathan A, Epstein
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A Syndrome of the Neural Crest

Archives of Neurology, 1966
IN THE past few years a number of cases have been described under the general heading of congenital insensitivity to pain with anhidrosis. In the present article an additional case is reported and a defect in neural crest differentiation proposed as the common underlying embryonic abnormality.
J W, Brown, R, Podosin
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Cardiac Neural Crest

Cold Spring Harbor Perspectives in Biology, 2020
Cardiac neural crest (CNC) cells are pluripotent cells derived from the dorsal neural tube that migrate and contribute to the remodeling of pharyngeal arch arteries and septation of the cardiac outflow tract (OFT). Numerous molecular cascades regulate the induction, specification, delamination, and migration of the CNC.
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Development of the neural crest

Current Opinion in Genetics & Development, 1991
Mutations that affect the morphogenetic behaviour and differentiation of neural crest-derived cells in mouse embryos have been shown to alter genes that code for growth factors or growth factor receptors. Identification of these and other gene products provide opportunities to understand when and how developmentally distinct embryonic cell populations ...
M F, Marusich, J A, Weston
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Evolutionary Origins of the Neural Crest and Neural Crest Cells

Evolutionary Biology, 2008
I evaluate the lines of evidence—cell types, genes, gene pathways, fossils—in putative chordate ancestors—cephalochordates and ascidians—pertaining to the evolutionary origin of the vertebrate neural crest. Given the intimate relationship between the neural crest and the dorsal nervous system during development, I discuss the dorsal nervous system in ...
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Morphogenesis of the Neural Crest

1986
The vertebrate neural crest has been, and continues to be, the subject of active investigation, because it offers developmental biologists a unique model system with which to study control of morphogenesis as well as cellular differentiation. Neural crest cells migrate great distances in the embryo and move along many diverse pathways.
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The neural crest in vertebrate evolution

Current Opinion in Genetics & Development, 2012
Vertebrates belong to the group of chordates characterized by a dorsal neural tube and an anteroposterior axis, the notochord. They are the only chordates to possess an embryonic and pluripotent structure associated with their neural primordium, the neural crest (NC).
Nicole M, Le Douarin, Elisabeth, Dupin
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