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Cardiac neural crest

Seminars in Cell & Developmental Biology, 2005
Neural crest cells (NCCs) contribute to many organs and tissues during embryonic development. Amongst these, the cardiovascular system represents a fascinating example. In this review, recent advances in our understanding of the developmental biology and molecular genetics regulating cardiac NCC maturation will be summarized.
Jason Z, Stoller, Jonathan A, Epstein
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The neural crest

Development, 2013
The neural crest (NC) is a highly migratory multipotent cell population that forms at the interface between the neuroepithelium and the prospective epidermis of a developing embryo. Following extensive migration throughout the embryo, NC cells eventually settle to differentiate into multiple cell types, ranging from neurons and glial cells of the ...
Roberto, Mayor, Eric, Theveneau
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Cardiac Neural Crest

Cold Spring Harbor Perspectives in Biology, 2020
Cardiac neural crest (CNC) cells are pluripotent cells derived from the dorsal neural tube that migrate and contribute to the remodeling of pharyngeal arch arteries and septation of the cardiac outflow tract (OFT). Numerous molecular cascades regulate the induction, specification, delamination, and migration of the CNC.
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Familial neural crest tumours

European Journal of Pediatrics, 1991
It is known that some cases of neural crest tumours are hereditary. We report the clinical and cytogenetic findings in a three-generation, extended family, four members of which developed single or multiple neural crest tumours (ganglioneuroma, ganglioneuroblastoma or neuroblastoma).
C M, Robertson   +2 more
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Neural Crest Stem Cells

2007
Stem cells are defined by their ability to both self-renew and give rise to multiple lineages in vivo and/or in vitro. As discussed in other chapters in this volume, the embryonic neural crest is a multipotent tissue that gives rise to a plethora of differentiated cell types in the adult organism and is unique to vertebrate embryos.
Lu, Teng, Patricia A, Labosky
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Neural Crest Inducing Signals

2007
The formation of the neural crest has been traditionally considered a classic example of secondary induction, where signals form one tissue elicit a response in a competent responding tissue. Interactions of the neural plate with paraxial mesoderm or nonneural ectoderm can generate neural crest. Several signaling pathways converge at the border between
Basch, Martín L.   +1 more
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Extended Multipotency of Neural Crest Cells and Neural Crest-Derived Cells

2015
Neural crest cells (NCC) are migratory multipotent cells that give rise to diverse derivatives. They generate various cell types during embryonic development, including neurons and glial cells of the peripheral sensory and autonomic ganglia, Schwann cells, melanocytes, endocrine cells, smooth muscle, and skeletal and connective tissue cells of the ...
Tsutomu, Motohashi, Takahiro, Kunisada
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The Neural Crest

1999
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a ...
Nicole Le Douarin, Chaya Kalcheim
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Neural Crest Development

2003
Neural crest arises at the interface of the ectoderm and neural tissue via inductive interactions between the two tissues (Fig. 8; Rosenquist 1981; Moury and Jacobson 1990; Selleck and Bronner-Fraser 1995; Mancilla and Mayor 1996). In fact, placement of the ectoderm and the neural plate together in in vivo or in vitro recombination assays can induce ...
P. H. Francis-West   +2 more
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Neural crest diversification.

Current topics in developmental biology, 1999
This chapter discusses some of the basic principles that have emerged from the study of neural crest biology. It discusses the origin of the neural crest in the embryo and considers some of the general principles underlying neural crest diversification.
Groves, Andrew K.   +1 more
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