Results 121 to 130 of about 4,393,966 (332)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Slow feature analysis yields a rich repertoire of complex cell properties [PDF]
, 2003 In this study, we investigate temporal slowness as a learning principle for receptive fields using slow feature analysis, a new algorithm to determine functions that extract slowly varying signals from the input data.
Berkes, Pietro, Wiskott, Laurenz
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
PLoS ONE, 2015 BackgroundPrevious studies have presented mixed findings on the inhibition ability in restrained eaters (REs) due to the limited amount of neural evidence and limitations of behavioral measures.
Fanchang Kong, Yan Zhang, Hong Chen
doaj +1 more source
Neural Activities Classification of Human Inhibitory Control Using Hierarchical Model
Sensors, 2019 Human inhibitory control refers to the suppression of behavioral response in real environments, such as when driving a car or riding a motorcycle, playing a game and operating a machine.
Rupesh Kumar Chikara, Li-Wei Ko
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Artificial Neural Nets with Interaction of Afferents [PDF]
, 2011 The aim is to obtain computationally more powerful, neuro physiologically founded, artificial neurons and neural nets. Artificial Neural Nets (ANN) of the Perceptron type evolved from the original proposal by McCulloch an Pitts classical paper [1 ...
Blasio, Gabriel de +2 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Neural Regeneration Research, 2016 Spontaneous axonal regeneration of neurons does not occur after spinal cord injury because of inhibition by myelin and other inhibitory factors. Studies have demonstrated that blocking the Rho/Rho-kinase (ROCK) pathway can promote neurite outgrowth in ...
Xu-feng Jia +3 more
doaj +1 more source
A Reconfigurable Mixed-signal Implementation of a Neuromorphic ADC
, 2015 We present a neuromorphic Analogue-to-Digital Converter (ADC), which uses integrate-and-fire (I&F) neurons as the encoders of the analogue signal, with modulated inhibitions to decohere the neuronal spikes trains. The architecture consists of an analogue
Hamilton, Tara Julia +5 more
core +1 more source