Results 111 to 120 of about 4,393,966 (332)

Global Neural Activities Changes under Human Inhibitory Control Using Translational Scenario

open access: yesBrain Sciences, 2020
This study presents a new approach to exploring human inhibition in a realistic scenario. In previous inhibition studies, the stimulus design of go/no-go task generally used a simple symbol for the go and stop signals.
Rupesh Kumar Chikara, Li-Wei Ko
doaj   +1 more source

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

open access: yesStem Cell Reports, 2017
Summary Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms.
James O. S. Hackland   +6 more
semanticscholar   +1 more source

Neural Evidence for Feature-based Distractor Inhibition

open access: yesJournal of Cognitive Neuroscience
Abstract Interference from a salient distractor is typically reduced when the appearance of the distractor follows either spatial or feature-based regularities. Although there is a growing body of literature on distractor location learning, the understanding of distractor feature learning remains limited.
Aylin A. Hanne, Sizhu Han, Anna Schubö
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Anxiety-Like Behavioural Inhibition Is Normative under Environmental Threat-Reward Correlations.

open access: yesPLoS Computational Biology, 2015
Behavioural inhibition is a key anxiety-like behaviour in rodents and humans, distinct from avoidance of danger, and reduced by anxiolytic drugs. In some situations, it is not clear how behavioural inhibition minimises harm or maximises benefit for the ...
Dominik R Bach
doaj   +1 more source

Ethanol inhibits neural cell-cell adhesion.

open access: yesJournal of Biological Chemistry, 1994
Gestational exposure to ethanol causes defects in neuronal migration, fasciculation, and synaptogenesis, developmental events that depend on the patterned expression and function of cell adhesion molecules (CAMs). Recombinant human osteogenic protein-1 (hOP-1) increases cell-cell adhesion and promotes cell clustering in proliferating neuroblastoma x ...
M E, Charness, R M, Safran, G, Perides
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The role of competitive inhibition and top-down feedback in binding during object recognition

open access: yesFrontiers in Psychology, 2012
How does the brain bind together visual features that are processed concurrently by different neurons into a unified percept suitable for processes such as object recognition?
Dean eWyatte   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Stage-specific roles of FGF2 signaling in human neural development

open access: yesStem Cell Research, 2016
This study elucidated the stage-specific roles of FGF2 signaling during neural development using in-vitro human embryonic stem cell-based developmental modeling.
Marta Grabiec   +6 more
doaj   +1 more source

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