Results 111 to 120 of about 2,658,546 (298)
Ontogeny of neural circuits underlying spatial memory in the rat [PDF]
, 2012 Spatial memory is a well-characterized psychological function in both humans and rodents. The combined computations of a network of systems including place cells in the hippocampus, grid cells in the medial entorhinal cortex and head direction cells ...
Langston, Rosamund F.; id_orcid +7 more
core +1 more source
Anxiety-Like Behavioural Inhibition Is Normative under Environmental Threat-Reward Correlations.
PLoS Computational Biology, 2015 Behavioural inhibition is a key anxiety-like behaviour in rodents and humans, distinct from avoidance of danger, and reduced by anxiolytic drugs. In some situations, it is not clear how behavioural inhibition minimises harm or maximises benefit for the ...
Dominik R Bach
doaj +1 more source
The role of competitive inhibition and top-down feedback in binding during object recognition
Frontiers in Psychology, 2012 How does the brain bind together visual features that are processed concurrently by different neurons into a unified percept suitable for processes such as object recognition?
Dean eWyatte +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Stage-specific roles of FGF2 signaling in human neural development
Stem Cell Research, 2016 This study elucidated the stage-specific roles of FGF2 signaling during neural development using in-vitro human embryonic stem cell-based developmental modeling.
Marta Grabiec +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A bilateral cortico-bulbar network associated with breath holding in humans, determined by functional magnetic resonance imaging [PDF]
, 2008 Few tasks are simpler to perform than a breath hold; however, the neural basis underlying this voluntary inhibitory behaviour, which must suppress spontaneous respiratory motor output, is unknown.
Frackowiak, Richard S J +6 more
core +1 more source
PTEN inhibition and axon regeneration and neural repair
Neural Regeneration Research, 2015 The intrinsic growth ability of all the neurons declines during development although some may grow better than others. Numerous intracellular signaling proteins and transcription factors have been shown to regulate the intrinsic growth capacity in mature neurons. Among them, PI3 kinase/Akt pathway is important for controlling axon elongation.
Yosuke Ohtake, Umar Hayat, Shuxin Li
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Neural Activities Classification of Human Inhibitory Control Using Hierarchical Model
Sensors, 2019 Human inhibitory control refers to the suppression of behavioral response in real environments, such as when driving a car or riding a motorcycle, playing a game and operating a machine.
Rupesh Kumar Chikara, Li-Wei Ko
doaj +1 more source