ERP correlates of forgetting: an investigation of resource allocation as a potential neural mechanism behind retrieval-induced forgetting [PDF]
, 2012 The present study was aimed at investigating a potential mechanism behind retrieval-induced forgetting that we have termed resource allocation. Three experiments were designed around the notion that increasing the number memories associated with one ...
Walters, Marie
core +2 more sources
Neural correlates of central inhibition during physical fatigue. [PDF]
PLoS ONE, 2013 Central inhibition plays a pivotal role in determining physical performance during physical fatigue. Classical conditioning of central inhibition is believed to be associated with the pathophysiology of chronic fatigue.
Masaaki Tanaka +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
How feedback inhibition shapes spike-timing-dependent plasticity and its implications for recent Schizophrenia models [PDF]
, 2011 It has been shown that plasticity is not a fixed property but, in fact, changes depending on the location of the synapse on the neuron and/or changes of biophysical parameters.
Di Prodi, P. +18 more
core +1 more source
Suppression and facilitation of human neural responses
eLife, 2018 Efficient neural processing depends on regulating responses through suppression and facilitation of neural activity. Utilizing a well-known visual motion paradigm that evokes behavioral suppression and facilitation, and combining five different ...
Michael-Paul Schallmo +7 more
doaj +1 more source
Regulating synchronous oscillations of cerebellar granule cells by different types of inhibition.
PLoS Computational Biology, 2021 Synchronous oscillations in neural populations are considered being controlled by inhibitory neurons. In the granular layer of the cerebellum, two major types of cells are excitatory granular cells (GCs) and inhibitory Golgi cells (GoCs).
Yuanhong Tang +3 more
doaj +1 more source
P3 as a neural index of response inhibition. [PDF]
, 2015 This study aimed to identify which ERP are specifically related to response inhibition. Electrophysiological activity was recorded from 30 subjects, and was submitted to a temporospatial principal component analysis to detect and quantify the main components associated with response inhibition.
Lopez-Martin, Sara +4 more
openaire +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source