Results 91 to 100 of about 4,393,966 (332)

Dissociation between cortical and spinal excitability of the antagonist muscle during combined motor imagery and action observation

Scientific Reports, 2019
Inhibitory neural control of antagonist muscle is one of the fundamental neural mechanism of coordinated human limb movement. Previous studies have revealed that motor execution (ME) and motor imagery (MI) share many common neural substrates; however ...
Toshiyuki Aoyama, Fuminari Kaneko, Yukari Ohashi, Yutaka Kohno   +3 more
doaj   +1 more source

Inhibition, Shifting and Updating: Inter and intra-domain commonalities and differences from an executive functions activation likelihood estimation meta-analysis

NeuroImage, 2022
Executive functions are higher-order mental processes that support goal-directed behavior. Among these processes, Inhibition, Updating, and Shifting have been considered core executive domains.
Geraldine Rodríguez-Nieto, Caroline Seer, Justina Sidlauskaite, Lore Vleugels, Anke Van Roy, Robert Hardwick, Stephan Swinnen   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Transcriptomic profiling of neural cultures from the KYOU iPSC line via alternative differentiation protocols

Frontiers in Molecular Neuroscience
The differentiation of pluripotent stem cells into neurons is an essential area of biomedical research, with significant implications for understanding neural development and treating neurological diseases.
Adelya Galiakberova, Sergey Ivanov, Sergey Ivanov, Arkadiy Golov, Alexander Artyuhov, Alexander Artyuhov, Alexey Zolkin, Alexey Zolkin, Nikolay Kondratyev, Alexey Lagunin, Alexey Lagunin, Vera Golimbet, Erdem Dashinimaev, Erdem Dashinimaev, Erdem Dashinimaev, Erdem Dashinimaev   +15 more
doaj   +1 more source

Neural correlates of central inhibition during physical fatigue. [PDF]

PLoS ONE, 2013
Central inhibition plays a pivotal role in determining physical performance during physical fatigue. Classical conditioning of central inhibition is believed to be associated with the pathophysiology of chronic fatigue.
Masaaki Tanaka, Akira Ishii, Yasuyoshi Watanabe   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Suppression and facilitation of human neural responses

eLife, 2018
Efficient neural processing depends on regulating responses through suppression and facilitation of neural activity. Utilizing a well-known visual motion paradigm that evokes behavioral suppression and facilitation, and combining five different ...
Michael-Paul Schallmo, Alexander M Kale, Rachel Millin, Anastasia V Flevaris, Zoran Brkanac, Richard AE Edden, Raphael A Bernier, Scott O Murray   +7 more
doaj   +1 more source

Regulating synchronous oscillations of cerebellar granule cells by different types of inhibition.

PLoS Computational Biology, 2021
Synchronous oscillations in neural populations are considered being controlled by inhibitory neurons. In the granular layer of the cerebellum, two major types of cells are excitatory granular cells (GCs) and inhibitory Golgi cells (GoCs).
Yuanhong Tang, Lingling An, Quan Wang, Jian K Liu   +3 more
doaj   +1 more source

Engaging and disengaging recurrent inhibition coincides with sensing and unsensing of a sensory stimulus [PDF]

, 2017
Even simple sensory stimuli evoke neural responses that are dynamic and complex. Are the temporally patterned neural activities important for controlling the behavioral output? Here, we investigated this issue.
Altan, Ege, Barbour, Dennis L, Chen, Alex, Chen, Zhengdao, Li, Chao, Lo, Ray, Nizampatnam, Srinath, Padovano, William, Raman, Baranidharan, Saha, Debajit, Sun, Wensheng   +10 more
core   +2 more sources

Neural induction - Dual SMAD inhibition

StemBook, 2014
Dual SMAD inhibition takes a confluent, feeder free culture of hPSCs and rapidly differentiates them into early neurectoderm (Chambers et al., 2009). This rapid differentiation is caused by blocking the two signaling pathways that utilize SMADs for transduction: BMP and TGFB.
openaire   +1 more source