Results 81 to 90 of about 4,393,966 (332)
International Journal of Psychophysiology, 2019 The stop-signal task (SST) is used to study action-stopping in the laboratory. In SSTs, the P3 event-related potential following stop-signals is considered to be a neural index of motor inhibition.
Darcy A. Waller, E. Hazeltine, J. Wessel
semanticscholar +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Contralateral inhibition of click- and chirp-evoked human compound action potentials [PDF]
, 2017 Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is ...
Cone, Barbara K +2 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A modified neural network model for Lobula Giant Movement Detector with additional depth movement feature [PDF]
, 2009 The Lobula Giant Movement Detector (LGMD) is a wide-field visual neuron that is located in the Lobula layer of the Locust nervous system. The LGMD increases its firing rate in response to both the velocity of the approaching object and its proximity.
Appiah, Kofi +7 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Advanced ScienceInhibition is an important concept in cognitive neuroscience. Direct inhibition, characterized by the active suppression of stimuli, and competition‐induced inhibition, which involves ignoring irrelevant stimuli by prioritizing relevant ones, have ...
Zhenhong He +6 more
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Research on Lateral Inhibition Network Based on Cell Membrane Electrical Model
PhotonicsLateral inhibition is a prevalent occurrence within the biological neural system, enhancing the human brain’s ability to perceive edge information within a given scene.
Dao-Han Qi, Ming-Jie Sun, Qing-Zhong Cai
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Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source